(Q33755811)

English

Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

haploinsufficiency

0 references

Constantine A Stratakis

13

object named as

Constantine A Stratakis

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Madson Q Almeida

1

object named as

Madson Q Almeida

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Michael Muchow

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Sosipatros Boikos

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Andrew J Bauer

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Kurt J Griffin

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Kit Man Tsang

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Chris Cheadle

7

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Tonya Watkins

8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Feng Wen

9

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Matthew F Starost

10

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ioannis Bossis

11

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Maria Nesterova

12

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

publication date

15 January 2010

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Human Molecular Genetics

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

19

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1387-1398

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumourigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Clinical and genetic heterogeneity, overlap with other tumor syndromes, and atypical glucocorticoid hormone secretion in adrenocorticotropin-independent macronodular adrenal hyperplasia compared with other adrenocortical tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Regulatory subunits of PKA define an axis of cellular proliferation/differentiation in ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

An immortalized human cell line bearing a PRKAR1A-inactivating mutation: effects of overexpression of the wild-type Allele and other protein kinase A subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Pituitary-specific knockout of the Carney complex gene Prkar1a leads to pituitary tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Serial analysis of gene expression in adrenocortical hyperplasia caused by a germline PRKAR1A mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Java Treeview--extensible visualization of microarray data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Gene array analysis of macronodular adrenal hyperplasia confirms clinical heterogeneity and identifies several candidate genes as molecular mediators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Analysis of microarray data using Z score transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

The cadherin-catenin adhesion system in signaling and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the carney complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Mouse tumor model for neurofibromatosis type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Mouse models of tumor development in neurofibromatosis type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Cluster analysis and display of genome-wide expression patterns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Identification of differentially expressed genes in chemically induced skin tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Tumor spectrum analysis in p53-mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

The complex of myxomas, spotty pigmentation, and endocrine overactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Effects of an Rb mutation in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

28 July 2018

Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Loss of expression of protein kinase a regulatory subunit 1alpha in pigmented epithelioid melanocytoma but not in melanoma or other melanocytic lesions.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Protein kinase-A activity in PRKAR1A-mutant cells, and regulation of mitogen-activated protein kinases ERK1/2.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD).

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Development of a pituitary-specific cre line targeted to the Pit-1 lineage.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Comparison of chemical carcinogen skin tumor induction efficacy in inbred, mutant, and hybrid strains of mice: morphologic variations of induced tumors and absence of a papillomavirus cocarcinogen.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

The E2F1-3 transcription factors are essential for cellular proliferation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Convergence of 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A and glycogen synthase kinase-3beta/beta-catenin signaling in corpus luteum progesterone synthesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Required roles of Bax and JNKs in central and peripheral nervous system death of retinoblastoma-deficient mice.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Protein kinase A isozyme switching: eliciting differential cAMP signaling and tumor reversion.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846157

30 October 2018

Malignant conversion of mouse skin tumours is increased by tumour initiators and unaffected by tumour promoters

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ014

21 January 2018

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20080939

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated onsets of gastric hamartomas and hepatic adenomas/carcinomas in Lkb1+/-p53-/- compound mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20080939

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumor promoter, 12-O-tetradecanoylphorbol-13-acetate accelerates keratinocyte differentiation and stimulates growth of an unidentified cell type in cultured human epidermis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20080939

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/20080939

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt/beta-catenin and 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A signaling pathways alterations and somatic beta-catenin gene mutations in the progression of adrenocortical tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20080939

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDQ014

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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