(Q39017137)

8 September 2017

title

Functional role of asparaginyl endopeptidase ubiquitination by TRAF6 in tumor invasion and metastasis (English)

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8 September 2017

main subject

protein ubiquitination

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Yingying Lin

1

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8 September 2017

Yongming Qiu

2

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8 September 2017

Cheng Xu

3

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8 September 2017

Qiaoling Liu

4

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8 September 2017

Baowei Peng

5

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8 September 2017

Gunnar F Kaufmann

6

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8 September 2017

Xi Chen

7

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8 September 2017

Bin Lan

8

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8 September 2017

Chongyang Wei

9

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8 September 2017

Desheng Lu

10

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8 September 2017

Yueshan Zhang

11

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8 September 2017

Yifeng Guo

12

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8 September 2017

Zhimin Lu

13

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8 September 2017

Biao Jiang

14

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8 September 2017

Thomas S Edgington

15

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8 September 2017

Fang Guo

16

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8 September 2017

language of work or name

English

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publication date

7 March 2014

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Journal of the National Cancer Institute

8 September 2017

published in

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8 September 2017

volume

106

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8 September 2017

issue

4

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8 September 2017

page(s)

dju012

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Unraveling the role of proteases in cancer

8 September 2017

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An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

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Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase

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Identification of human asparaginyl endopeptidase (legumain) as an inhibitor of osteoclast formation and bone resorption

21 January 2018

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Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis

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Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells

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Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.

21 January 2018

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Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase

21 January 2018

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Legumain expression in relation to clinicopathologic and biological variables in colorectal cancer

21 January 2018

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Legumain expression as a prognostic factor in breast cancer patients.

21 January 2018

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21 January 2018

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21 January 2018

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Ubiquitin enters the new millennium

21 January 2018

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

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The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

21 January 2018

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TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor

21 January 2018

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The E3 ligase TRAF6 regulates Akt ubiquitination and activation

21 January 2018

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TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

21 January 2018

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The landscape of somatic copy-number alteration across human cancers

21 January 2018

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The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review

21 January 2018

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Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness

21 January 2018

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The regulatory mechanism of Hsp90alpha secretion and its function in tumor malignancy

21 January 2018

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Targeting tumor-associated macrophages as a novel strategy against breast cancer

21 January 2018

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Legumain and cathepsin-L expression in human unstable carotid plaque.

21 January 2018

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Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo

21 January 2018

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Cloning and expression of mouse legumain, a lysosomal endopeptidase

21 January 2018

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Distinct molecular mechanism for initiating TRAF6 signalling

21 January 2018

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The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL

21 January 2018

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Defining the human deubiquitinating enzyme interaction landscape

21 January 2018

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Aza-peptide epoxides: potent and selective inhibitors of Schistosoma mansoni and pig kidney legumains (asparaginyl endopeptidases).

21 January 2018

1 reference

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Blastocystis legumain is localized on the cell surface, and specific inhibition of its activity implicates a pro-survival role for the enzyme

21 January 2018

1 reference

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A census of human soluble protein complexes

21 January 2018

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Nucleoplasmic calcium regulates cell proliferation through legumain

21 January 2018

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Sorting of lysosomal proteins

21 January 2018

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Intra- and extracellular regulation of activity and processing of legumain by cystatin E/M.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/JNCI/DJU012

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8 September 2017

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