(Q34320916)

1 August 2017

title

Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis (English)

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1 August 2017

1 reference

Enrico Giraudo

5

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Douglas Hanahan

object named as

Douglas Hanahan

10

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Matthew Bogyo

9

object named as

Matthew Bogyo

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1 August 2017

Johanna A Joyce

1

1 reference

1 August 2017

Amos Baruch

2

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1 August 2017

Kareem Chehade

3

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1 August 2017

Nicole Meyer-Morse

4

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1 August 2017

Fong-Ying Tsai

6

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1 August 2017

Doron C Greenbaum

7

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1 August 2017

Jeffrey H Hager

8

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1 August 2017

language of work or name

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1 May 2004

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1 August 2017

number of pages

11

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inferred from page(s)

published in

Cancer Cell

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1 August 2017

volume

5

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1 August 2017

issue

5

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1 August 2017

page(s)

443-453

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Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice

1 August 2017

cites work

1 reference

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Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation

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Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

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7 January 2021

Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs

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7 January 2021

In vivo molecular target assessment of matrix metalloproteinase inhibition

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7 January 2021

Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues

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7 January 2021

Angiogenesis in health and disease

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A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis

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Inflammation and cancer

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Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha

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7 January 2021

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

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7 January 2021

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

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7 January 2021

Induction of angiogenesis during the transition from hyperplasia to neoplasia

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7 January 2021

Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

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7 January 2021

Chemical approaches for functionally probing the proteome

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7 January 2021

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

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7 January 2021

Decreased metastatic spread in mice homozygous for a null allele of the cystatin C protease inhibitor gene

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7 January 2021

VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis

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7 January 2021

Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts

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Basement membranes: structure, assembly and role in tumour angiogenesis

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Lessons from hereditary colorectal cancer

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7 January 2021

Unraveling the role of proteases in cancer

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7 January 2021

Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B.

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7 January 2021

Modulation of cystatin C expression impairs the invasive and tumorigenic potential of human glioblastoma cells

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7 January 2021

Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis

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7 January 2021

Cysteine protease inhibitors as chemotherapy for parasitic infections

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7 January 2021

Mechanistic studies on the inactivation of papain by epoxysuccinyl inhibitors

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7 January 2021

The rise and fall of apoptosis during multistage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors

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7 January 2021

A causal role for E-cadherin in the transition from adenoma to carcinoma

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7 January 2021

Molecular mechanisms of glioma invasiveness: the role of proteases

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7 January 2021

The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cells

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7 January 2021

Pericellular cathepsin B and malignant progression

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7 January 2021

Deficiency of the cysteine protease cathepsin S impairs microvessel growth

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7 January 2021

Epigenetic versus genetic alterations in the inactivation of E-cadherin

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7 January 2021

Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation

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7 January 2021

Lysosomal cysteine proteases: facts and opportunities

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7 January 2021

Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer

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7 January 2021

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

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7 January 2021

Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.

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7 January 2021

10.1016/S1535-6108(04)00111-4

Identifiers

DOI

1 reference

1 August 2017

1 reference