(Q39019022)

8 September 2017

Efficacy of intermittent combined RAF and MEK inhibition in a patient with concurrent BRAF- and NRAS-mutant malignancies (English)

1 reference

8 September 2017

1 reference

1 reference

ChEBI release 2020-05-28

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Eunhee Kim

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Virginia M Klimek

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Alisa A Gaskell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Agnes Viale

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Donavan Cheng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Raajit Rampal

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Mark Bluth

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

James J Harding

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Margaret K Callahan

10

1 reference

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8 June 2020

Taha Merghoub

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Michael F Berger

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

David B Solit

13

1 reference

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8 June 2020

Neal Rosen

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Ross L Levine

15

1 reference

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8 June 2020

Paul B Chapman

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

3 March 2014

1 reference

8 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

538-545

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

8 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

High-throughput droplet digital PCR system for absolute quantitation of DNA copy number

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

A framework for variation discovery and genotyping using next-generation DNA sequencing data

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Fast and accurate short read alignment with Burrows-Wheeler transform

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Preclinical disposition of GDC-0973 and prospective and retrospective analysis of human dose and efficacy predictions

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

The digital MIQE guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Progression of RAS-mutant leukemia during RAF inhibitor treatment

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

Prognostic score including gene mutations in chronic myelomonocytic leukemia.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4850735

10.1158/2159-8290.CD-13-1038

21 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24589925%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference