(Q39023402)

English

Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2.

scientific article published on June 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2. (English)

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

1 reference

based on heuristic

inferred from title

Human Induced Pluripotent Stem Cells

1 reference

based on heuristic

inferred from title

author name string

M Joseph Phillips

1

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Europe PubMed Central

PMC publication ID

8 September 2017

Enio T Perez

2

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Europe PubMed Central

PMC publication ID

8 September 2017

Jessica M Martin

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Samantha T Reshel

4

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Kyle A Wallace

5

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Europe PubMed Central

PMC publication ID

8 September 2017

Elizabeth E Capowski

6

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Ruchira Singh

7

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Lynda S Wright

8

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Eric M Clark

9

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Patrick M Barney

10

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Ron Stewart

11

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Sarah J Dickerson

12

1 reference

Europe PubMed Central

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8 September 2017

Michael J Miller

13

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

E Ferda Percin

14

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

James A Thomson

15

1 reference

Europe PubMed Central

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8 September 2017

David M Gamm

16

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

publication date

1 June 2014

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Europe PubMed Central

PMC publication ID

8 September 2017

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

32

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Europe PubMed Central

PMC publication ID

8 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

1480-1492

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Retinal pigment epithelium development, plasticity, and tissue homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Functional analysis of serially expanded human iPS cell-derived RPE cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

A simple and scalable process for the differentiation of retinal pigment epithelium from human pluripotent stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Otx but not Mitf transcription factors are required for zebrafish retinal pigment epithelium development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Self-formation of optic cups and storable stratified neural retina from human ESCs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Embryonic stem cell trials for macular degeneration: a preliminary report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

VSX2 mutations in autosomal recessive microphthalmia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Eye morphogenesis and patterning of the optic vesicle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Eye Development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Derivation of induced pluripotent stem cells from human peripheral blood T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Generation, purification and transplantation of photoreceptors derived from human induced pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Modeling early retinal development with human embryonic and induced pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Vsx2 in the zebrafish retina: restricted lineages through derepression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Identification of novel mutations and sequence variants in the SOX2 and CHX10 genes in patients with anophthalmia/microphthalmia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Alternative promoter use in eye development: the complex role and regulation of the transcription factor MITF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

The developing and evolving retina: using time to organize form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Mutations in the CHX10 gene in non-syndromic microphthalmia/anophthalmia patients from Qatar

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Focus on molecules: homeobox protein Chx10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Molecular mechanisms of optic vesicle development: complexities, ambiguities and controversies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Secreted inducers in vertebrate eye development: more functions for old morphogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Eye development: a view from the retina pigmented epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Regulation of proliferation, cell fate specification and differentiation by the homeodomain proteins Prox1, Six3, and Chx10 in the developing retina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Human microphthalmia associated with mutations in the retinal homeobox gene CHX10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Embryology of the eye and its adnexae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Nonxenogeneic growth and retinal differentiation of human induced pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

9 September 2017

Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

14 September 2017

Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

17 June 2018

Inactivation of the zebrafish homologue of Chx10 by antisense oligonucleotides causes eye malformations similar to the ocular retardation phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

17 June 2018

Brief report: self-organizing neuroepithelium from human pluripotent stem cells facilitates derivation of photoreceptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

Fgf19 is required for zebrafish lens and retina development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

Delayed expression of the Crx gene and photoreceptor development in the Chx10-deficient retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

Genetic rescue of cell number in a mouse model of microphthalmia: interactions between Chx10 and G1-phase cell cycle regulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

Patterning the optic neuroepithelium by FGF signaling and Ras activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

Fibroblast growth factors are necessary for neural retina but not pigmented epithelium differentiation in chick embryos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037340

21 August 2018

Cell fate determination in the vertebrate retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/24532057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partial rescue of the ocular retardation phenotype by genetic modifiers

1 reference

https://pubmed.ncbi.nlm.nih.gov/24532057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extraocular mesenchyme patterns the optic vesicle during early eye development in the embryonic chick

1 reference

https://pubmed.ncbi.nlm.nih.gov/24532057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Otx genes are required for tissue specification in the developing eye

1 reference

https://pubmed.ncbi.nlm.nih.gov/24532057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of genetic modifiers affecting the eye phenotype of ocular retardation (Chx10or-J) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24532057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/STEM.1667

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

ResearchGate publication ID

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