(Q39026497)

English

Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector

scientific article published on 18 January 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector (English)

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

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author name string

Dennis Kobelt

1

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Jutta Aumann

2

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Manuel Schmidt

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Burghardt Wittig

4

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Iduna Fichtner

5

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Diana Behrens

6

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Margit Lemm

7

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Greta Freundt

8

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Peter M Schlag

9

1 reference

Europe PubMed Central

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8 September 2017

Wolfgang Walther

10

1 reference

Europe PubMed Central

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8 September 2017

publication date

18 January 2014

1 reference

Europe PubMed Central

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8 September 2017

Molecular Oncology

1 reference

Europe PubMed Central

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8 September 2017

8

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

609-619

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

20 years experience of TNF-based isolated limb perfusion for in-transit melanoma metastases: TNF dose matters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Long-term outcome of isolated limb perfusion with tumour necrosis factor-α for patients with melanoma in-transit metastases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Isolated limb perfusion for melanoma in-transit metastases: developments in recent years and the role of tumor necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Serious overestimation in quantitative PCR by circular (supercoiled) plasmid standard: microalgal pcna as the model gene

1 reference

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9 September 2017

Treatment for metastatic malignant melanoma: old drugs and new strategies

1 reference

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9 September 2017

TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice

1 reference

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9 September 2017

Use of minicircle plasmids for gene therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Cytokine-based therapy and biochemotherapy for advanced melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Biodistribution of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar, without Integration, despite Differing Plasmid Backbones or Gene Inserts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

The mechanism of naked DNA uptake and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Tumor necrosis factor, cancer and anticancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Signalling pathways of the TNF superfamily: a double-edged sword

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Synergistic antitumour effect of TNF-SAM2 with melphalan and doxorubicin in isolated limb perfusion in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

TNF alpha in isolated perfusion systems: success in the limb, developments for the liver credits, debits and future perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Isolated limb perfusion with high-dose tumor necrosis factor-alpha in combination with interferon-gamma and melphalan for nonresectable extremity soft tissue sarcomas: a multicenter trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Caffeine potentiates the lethality of tumour necrosis factor in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Major amputation for advanced malignant melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Performance of high quality minicircle DNA for in vitro and in vivo gene transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

Minicircle DNA electrotransfer for efficient tissue-targeted gene delivery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

9 September 2017

TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

14 September 2017

Tumor necrosis factor-alpha damages tumor blood vessel integrity by targeting VE-cadherin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

14 September 2017

Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

14 September 2017

TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

14 September 2017

A new DNA vehicle for nonviral gene delivery: supercoiled minicircle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

25 September 2017

Cytokine-mediated reversal of multidrug resistance

1 reference

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17 June 2018

Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

17 June 2018

Gene transfer of human TNF alpha into glioblastoma cells permits modulation of mdr1 expression and potentiation of chemosensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

17 June 2018

Chemo-immunotherapy of murine solid tumors: enhanced therapeutic effects by interleukin-2 combined with interferon alpha and the role of specific T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

17 June 2018

Intratumoral dispersion, retention, systemic biodistribution, and clearance of a small-size tumor necrosis factor-α-expressing MIDGE vector after nonviral in vivo jet-injection gene transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

Isolated limb infusion for malignant melanoma: predictors of response and outcome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

Novel jet-injection technology for nonviral intratumoral gene transfer in patients with melanoma and breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

Minimal size MIDGE vectors improve transgene expression in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

Heat-inducible in vivo gene therapy of colon carcinoma by human mdr1 promoter-regulated tumor necrosis factor-alpha expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

Uptake, biodistribution, and time course of naked plasmid DNA trafficking after intratumoral in vivo jet injection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

The CpG island searcher: a new WWW resource.

1 reference

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21 August 2018

Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

Pentoxifyllin attenuates the systemic inflammatory response induced during isolated limb perfusion with recombinant human tumor necrosis factor-alpha and melphalan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

Intratumoral low-volume jet-injection for efficient nonviral gene transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

A novel minimal-size vector (MIDGE) improves transgene expression in colon carcinoma cells and avoids transfection of undesired DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528640

21 August 2018

Control of tumour vascular permeability

1 reference

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21 August 2018

c-FLIP efficiently rescues TRAF-2-/- cells from TNF-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24503218

12 December 2020

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Augmentation of antitumor efficacy by the combination of actinomycin D with tumor necrosis factor-alpha and interferon-gamma on a melanoma model in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24503218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical applications of TNF-alpha in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24503218

12 December 2020

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inferred from PubMed ID database lookup

MIDGE/hNIS vaccination generates antigen-associated CD8+IFN-gamma+ T cells and enhances protective antitumor immunity

1 reference

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Protection against FIV challenge infection by genetic vaccination using minimalistic DNA constructs for FIV env gene and feline IL-12 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24503218

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Anti-tumor effects of tumor necrosis factor in combination with chemotherapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/24503218

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based on heuristic

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10.1016/J.MOLONC.2013.12.019

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Europe PubMed Central

PMC publication ID

8 September 2017

release_2dgklul5rjhyhdp2vae5lj4yoy

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https://api.fatcat.wiki/v0/release/2dgklul5rjhyhdp2vae5lj4yoy

24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

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