(Q39031925)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

title

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

genome-wide association study

5 April 2020

main subject

0 references

author

Natalie J. Prescott

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

David C Wilson

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Carl A Anderson

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

James A Traherne

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

K G Smith

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

14

Paul A Lyons

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

8

Jack Satsangi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

4

Richard B Gearry

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

3

Rebecca Roberts

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

10

Luke Jostins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

author name string

James C Lee

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Daniele Biasci

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

John C Mansfield

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Tariq Ahmad

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

UK IBD Genetics Consortium

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Miles Parkes

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

language of work or name

English

0 references

publication date

9 January 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

volume

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

page(s)

262-268

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 April 2020

genome-wide association study

1 reference

https://scigraph.springernature.com/pub.10.1038/ng.3755

inferred from title

exact match

0 references

cites work

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

An atlas of genetic correlations across human diseases and traits

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

The UK10K project identifies rare variants in health and disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Burden of risk variants correlates with phenotype of multiple sclerosis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Erosion of X Chromosome Inactivation in Human Pluripotent Cells Initiates with XACT Coating and Depends on a Specific Heterochromatin Landscape.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

SNPsea: an algorithm to identify cell types, tissues and pathways affected by risk loci

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

A general approach for haplotype phasing across the full spectrum of relatedness

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Differential effect of genetic burden on disease phenotypes in Crohn's disease and ulcerative colitis: analysis of a North American cohort

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Identification of expressed and conserved human noncoding RNAs

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

An expression atlas of human primary cells: inference of gene function from coexpression networks

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Multi-population classical HLA type imputation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

STAR: ultrafast universal RNA-seq aligner

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Data quality control in genetic case-control association studies.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

A map of human genome variation from population-scale sequencing

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Common disorders are quantitative traits

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

PLINK: a tool set for whole-genome association and population-based linkage analyses

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

A Bayesian measure of the probability of false discovery in genetic epidemiology studies

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Changes in clinical characteristics, course, and prognosis of inflammatory bowel disease during the last 5 decades: a population-based study from Copenhagen, Denmark.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Clustering of disease features within 512 multicase rheumatoid arthritis families

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Risk of early surgery for Crohn's disease: implications for early treatment strategies

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn's disease.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Multiple sclerosis in sibling pairs: an analysis of 250 families

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Clinical patterns of familial inflammatory bowel disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Long-term outcomes in rheumatoid arthritis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

The cellular basis for lack of antibody response to hepatitis B vaccine in humans

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Do Genetic Susceptibility Variants Associate with Disease Severity in Early Active Rheumatoid Arthritis?

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Improved whole-chromosome phasing for disease and population genetic studies

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Cochran-Armitage test versus logistic regression in the analysis of genetic association studies.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

PredictABEL: an R package for the assessment of risk prediction models

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Common disorders are quantitative traits

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5730041

T-cell activation in HLA-B8,DR3-positive individuals early antigen expression defect in vitro

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28067912

12 December 2020

inferred from PubMed ID database lookup

Power of selective genotyping in genetic association analyses of quantitative traits

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28067912

12 December 2020

inferred from PubMed ID database lookup

HLA-B8,DR3 phenotype and lymphocyte responses to phytohaemagglutinin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28067912

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NG.3755

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

PubMed publication ID

28067912

1 reference