(Q39034589)

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Identification of highly connected hub genes in the protective response program of human macrophages and microglia activated by alpha B-crystallin

scientific article published on 7 January 2017

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scholarly article

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Europe PubMed Central

8 September 2017

Identification of highly connected hub genes in the protective response program of human macrophages and microglia activated by alpha B-crystallin (English)

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Europe PubMed Central

8 September 2017

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9 June 2020

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9 June 2020

author name string

Malika Bsibsi

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9 June 2020

Wouter H Gerritsen

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9 June 2020

Hendrikus W G M Boddeke

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9 June 2020

Bart J L Eggen

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9 June 2020

Paul van der Valk

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9 June 2020

Markus Kipp

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9 June 2020

Johannes M van Noort

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9 June 2020

publication date

7 January 2017

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8 September 2017

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9 June 2020

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9 June 2020

460-473

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9 June 2020

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9 June 2020

Cyclooxygenase-1 and -2 differentially modulate lipopolysaccharide-induced blood-brain barrier disruption through matrix metalloproteinase activity

1 reference

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21 January 2018

Systemic augmentation of alphaB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation.

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Gene ontology: tool for the unification of biology

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The blood-brain barrier and immune function and dysfunction

1 reference

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21 January 2018

Alpha-B-crystallin induces an immune-regulatory and antiviral microglial response in preactive multiple sclerosis lesions

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21 January 2018

Innate defense regulator peptide 1018 protects against perinatal brain injury.

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Inflammasome-induced IL-1β secretion in microglia is characterized by delayed kinetics and is only partially dependent on inflammatory caspases.

1 reference

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21 January 2018

Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4

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21 January 2018

Cyclooxygenases-1 and -2 differentially modulate leukocyte recruitment into the inflamed brain

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21 January 2018

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

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21 January 2018

Neuroinflammation, COX-2, and ALS--a dual role?

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Eicosanoid storm in infection and inflammation

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IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

1 reference

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21 January 2018

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

1 reference

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21 January 2018

CD44 deficiency contributes to enhanced experimental autoimmune encephalomyelitis: a role in immune cells and vascular cells of the blood-brain barrier

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21 January 2018

The PD-1 pathway in tolerance and autoimmunity

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21 January 2018

A20 deficiency causes spontaneous neuroinflammation in mice

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Negative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases

1 reference

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21 January 2018

Regulation of macrophage function by adenosine

1 reference

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21 January 2018

VisANT: an integrative framework for networks in systems biology

1 reference

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

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21 January 2018

Beneficial effects of αB-crystallin in spinal cord contusion injury.

1 reference

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21 January 2018

WGCNA: an R package for weighted correlation network analysis

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21 January 2018

The dynamics of the LPS triggered inflammatory response of murine microglia under different culture and in vivo conditions.

1 reference

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21 January 2018

Is my network module preserved and reproducible?

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21 January 2018

Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity

1 reference

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21 January 2018

Mesenchymal stem cells inhibit lipopolysaccharide-induced inflammatory responses of BV2 microglial cells through TSG-6.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.23104

21 January 2018

Targeting cyclooxygenase-2 in depression is not a viable therapeutic approach and may even aggravate the pathophysiology underpinning depression

1 reference

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21 January 2018

Molecular chaperone alpha-crystallin prevents detrimental effects of neuroinflammation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.23104

21 January 2018

Strategies for aggregating gene expression data: the collapseRows R function

1 reference

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21 January 2018

Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases

1 reference

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21 January 2018

Biochemical characterization of the very long-chain fatty acid elongase ELOVL7.

1 reference

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21 January 2018

Transcriptional network dynamics in macrophage activation

1 reference

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21 January 2018

The programmed death-1 immune-suppressive pathway: barrier to antitumor immunity

1 reference

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21 January 2018

Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination

1 reference

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21 January 2018

Brain interleukin-15 in neuroinflammation and behavior

1 reference

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21 January 2018

Functional rescue of experimental ischemic optic neuropathy with αB-crystallin

1 reference

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21 January 2018

B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance

1 reference

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21 January 2018

A diverse range of gene products are effectors of the type I interferon antiviral response

1 reference

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21 January 2018

A dynamic network of transcription in LPS-treated human subjects

1 reference

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21 January 2018

Novel Role of TRPML2 in the Regulation of the Innate Immune Response

1 reference

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21 January 2018

Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.23104

21 January 2018

Therapeutic Intervention in Multiple Sclerosis with Alpha B-Crystallin: A Randomized Controlled Phase IIa Trial

1 reference

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21 January 2018

Dissecting interferon-induced transcriptional programs in human peripheral blood cells

1 reference

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21 January 2018

α-Crystallin protects RGC survival and inhibits microglial activation after optic nerve crush

1 reference

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21 January 2018

Cerebral interleukin-15 shows upregulation and beneficial effects in experimental autoimmune encephalomyelitis

1 reference

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21 January 2018

Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells.

1 reference

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21 January 2018

MiR-9 promotes microglial activation by targeting MCPIP1.

1 reference

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21 January 2018

Alpha-crystallin protected axons from optic nerve degeneration after crushing in rats

1 reference

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21 January 2018

Delineation of diverse macrophage activation programs in response to intracellular parasites and cytokines

1 reference

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21 January 2018

Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages

1 reference

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21 January 2018

Cross-linking of CD137 ligand modulates immune responses of thioglycollate-elicited mouse peritoneal macrophages

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

MCPIP: a key player in macrophage polarization

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.23104

7 January 2021

based on heuristic

inferred from DOI database lookup

Alphab-crystallin is a target for adaptive immune responses and a trigger of innate responses in preactive multiple sclerosis lesions

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.23104

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/GLIA.23104

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28063173%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28063173%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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