(Q39034930)

8 September 2017

title

Synthesis of new lipoic acid conjugates and evaluation of their free radical scavenging and neuroprotective activities (English)

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8 September 2017

5

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8 September 2017

Michael Smietana

6

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author name string

Maria Laura Bolognesi

1

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8 September 2017

Christian Bergamini

2

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8 September 2017

Romana Fato

3

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8 September 2017

Joël Oiry

4

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8 September 2017

publication date

12 May 2014

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Chemical Biology and Drug Design

8 September 2017

published in

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8 September 2017

volume

83

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8 September 2017

issue

6

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8 September 2017

page(s)

688-696

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Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential

8 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Alpha-lipoic acid prevents buthionine sulfoximine-induced cataract formation in newborn rats

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Elucidation of antioxidant activity of alpha-lipoic acid toward hydroxyl radical.

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Thioctic Acid and Dihydrolipoic Acid are Novel Antioxidants Which Interact With Reactive Oxygen Species

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Neuroprotective effects of alpha-lipoic acid and its positively charged amide analogue

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Multifunctional lipoic acid conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds

21 January 2018

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Multitarget-directed drug design strategy: a novel molecule designed to block epidermal growth factor receptor (EGFR) and to exert proapoptotic effects

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Neuroprotection by the metabolic antioxidant alpha-lipoic acid

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Novel lipoic acid analogues that inhibit nitric oxide synthase

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Novel potent inhibitors of lipid peroxidation with protective effects against reperfusion arrhythmias

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Synthesis of chroman analogues of lipoic acid and evaluation of their activity against reperfusion arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts

21 January 2018

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(R)-α-lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities

21 January 2018

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L-dopa- and dopamine-(R)-alpha-lipoic acid conjugates as multifunctional codrugs with antioxidant properties.

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Hybrid lipoic acid derivatives to attack prion disease on multiple fronts

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Lipoic acid, a lead structure for multi-target-directed drugs for neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Multitarget-directed ligands: innovative chemical probes and therapeutic tools against Alzheimer's disease

21 January 2018

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NAC/MEA conjugate: a new potent antioxidant which increases the GSH level in various cell lines

21 January 2018

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Synthesis and biological evaluation in human monocyte-derived macrophages of N-(N-acetyl-L-cysteinyl)-S-acetylcysteamine analogues with potent antioxidant and anti-HIV activities

21 January 2018

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Synthesis of new N-isobutyryl-L-cysteine/MEA conjugates: evaluation of their free radical-scavenging activities and anti-HIV properties in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

The increase in intra-macrophage thiols induced by new pro-GSH molecules directs the Th1 skewing in ovalbumin immunized mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Molecules altering the intracellular thiol content modulate NF-kB and STAT-1/IRF-1 signalling pathways and IL-12 p40 and IL-27 p28 production in murine macrophages

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12282

Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Elevation of glutathione as a therapeutic strategy in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Synthesis and characterization of new and potent alpha-lipoic acid derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Antioxidant activity applying an improved ABTS radical cation decolorization assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Prostaglandin E2 as an immunomodulating factor released in vitro by human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Advances in iron chelation: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Alpha-lipoic acid as a biological antioxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12282

21 January 2018

Identifiers

DOI

10.1111/CBDD.12282

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8 September 2017

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