(Q39046941)

8 September 2017

title

The stability of secreted, acid-labile H77/JFH-1 hepatitis C virus (HCV) particles is altered by patient isolate genotype 1a p7 sequences (English)

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8 September 2017

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6

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Mark Harris

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author name string

Elizabeth Atkins

1

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8 September 2017

Ranjitha Tatineni

2

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8 September 2017

Hui Li

3

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8 September 2017

David Gretch

4

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8 September 2017

language of work or name

English

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publication date

24 October 2013

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full work available at URL

8 September 2017

http://eprints.whiterose.ac.uk/77848/

content deliverer

White Rose Research Online

object has role

published version

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https://doi.org/10.1016/j.virol.2013.10.003

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8 September 2017

volume

448

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8 September 2017

page(s)

117-124

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Mutations in hepatitis C virus p7 reduce both the egress and infectivity of assembled particles via impaired proton channel function

8 September 2017

cites work

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Distinct roles in folding, CD81 receptor binding and viral entry for conserved histidine residues of hepatitis C virus glycoprotein E1 and E2.

7 January 2021

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A concerted action of hepatitis C virus p7 and nonstructural protein 2 regulates core localization at the endoplasmic reticulum and virus assembly

7 January 2021

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Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro

7 January 2021

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Structure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release

7 January 2021

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Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel

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Cellular Determinants of Hepatitis C Virus Assembly, Maturation, Degradation, and Secretion

7 January 2021

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Differential Biophysical Properties of Infectious Intracellular and Secreted Hepatitis C Virus Particles

7 January 2021

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hepatitis c Virus p7 is critical for capsid assembly and envelopment

7 January 2021

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Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A.

7 January 2021

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Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel

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The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine

7 January 2021

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A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria

7 January 2021

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Low pH-dependent Hepatitis C Virus Membrane Fusion Depends on E2 Integrity, Target Lipid Composition, and Density of Virus Particles

7 January 2021

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Structural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus Assembly

7 January 2021

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Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly

7 January 2021

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Hepatitis C virus glycoproteins mediate low pH-dependent membrane fusion with liposomes

7 January 2021

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Genetic and functional heterogeneity of the hepatitis C virus p7 ion channel during natural chronic infection

7 January 2021

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The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy

7 January 2021

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Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins

7 January 2021

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Hepatitis C virus-induced autophagy is independent of the unfolded protein response

7 January 2021

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Unusual architecture of the p7 channel from hepatitis C virus

7 January 2021

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The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives

7 January 2021

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Identification of the membrane-active regions of hepatitis C virus p7 protein: biophysical characterization of the loop region.

7 January 2021

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A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity

7 January 2021

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NS2 protein of hepatitis C virus interacts with structural and non-structural proteins towards virus assembly

7 January 2021

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Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride

7 January 2021

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Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes.

7 January 2021

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Hepatitis C virus NS2 coordinates virus particle assembly through physical interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes

7 January 2021

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7 January 2021

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7 January 2021

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Determinants of Hepatitis C Virus p7 Ion Channel Function and Drug Sensitivity Identified In Vitro

7 January 2021

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7 January 2021

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The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 protein

7 January 2021

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Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry

7 January 2021

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Subcellular localization and function of an epitope-tagged p7 viroporin in hepatitis C virus-producing cells

7 January 2021

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Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

7 January 2021

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High-risk human papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small-molecule inhibitors

7 January 2021

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Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production

7 January 2021

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Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus

7 January 2021

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10.1016/J.VIROL.2013.10.003

7 January 2021

Identifiers

DOI

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8 September 2017

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