(Q39066968)

8 September 2017

title

Bortezomib-induced apoptosis in cultured pancreatic cancer cells is associated with ceramide production (English)

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8 September 2017

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Lei Gong

1

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8 September 2017

Bo Yang

2

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8 September 2017

Ming Xu

3

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8 September 2017

Bo Cheng

4

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8 September 2017

Xuejun Tang

5

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8 September 2017

Ping Zheng

6

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8 September 2017

Yan Jing

7

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8 September 2017

Gao-jue Wu

8

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8 September 2017

publication date

5 November 2013

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Cancer Chemotherapy and Pharmacology

8 September 2017

published in

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8 September 2017

volume

73

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8 September 2017

issue

1

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8 September 2017

page(s)

69-77

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https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

8 September 2017

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21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Randomized phase III trial of gemcitabine plus cisplatin compared with single-agent gemcitabine as first-line treatment of patients with advanced pancreatic cancer: the GIP-1 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Pancreatic cancer in 2010: new insights for early intervention and detection

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1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Pancreatic cancer: molecular pathogenesis and new therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Preclinical and clinical development of the proteasome inhibitor bortezomib in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Bortezomib: proteasome inhibition as an effective anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

ER stress and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

A pivotal role for Mcl-1 in Bortezomib-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Down-regulation of phospho-Akt is a major molecular determinant of bortezomib-induced apoptosis in hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Ceramide in chemotherapy of tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Trojan-horse nanotube on-command intracellular drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Co-administration phenoxodiol with doxorubicin synergistically inhibit the activity of sphingosine kinase-1 (SphK1), a potential oncogene of osteosarcoma, to suppress osteosarcoma cell growth both in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Targeting SphK1 as a new strategy against cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

A phase 2 study of bortezomib in relapsed, refractory myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Ceramide and apoptosis: exploring the enigmatic connections between sphingolipid metabolism and programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

The multigenic sphingomyelin synthase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Ceramide in apoptosis signaling: relationship with oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

ASK1 is essential for JNK/SAPK activation by TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

Ceramide-orchestrated signalling in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-013-2318-3

10.1007/S00280-013-2318-3

21 January 2018

Identifiers

DOI

1 reference

8 September 2017

1 reference