(Q39073514)

30 June 2019

title

Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling (English)

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30 June 2019

author

Munetaka Iwata

4

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30 June 2019

author name string

Jinying Piao

1

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30 June 2019

Kunikazu Tsuji

2

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30 June 2019

Hiroki Ochi

3

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30 June 2019

Daisuke Koga

5

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30 June 2019

Atsushi Okawa

6

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30 June 2019

Sadao Morita

7

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30 June 2019

Shu Takeda

8

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30 June 2019

Yoshinori Asou

9

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language of work or name

English

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publication date

23 October 2013

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30 June 2019

published in

Scientific Reports

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30 June 2019

volume

3

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30 June 2019

page(s)

3022

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30 June 2019

Creative Commons Attribution 3.0 Unported

copyright license

start time

23 October 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

The Sir2 family of protein deacetylases

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Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

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Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6.

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Human SIRT6 promotes DNA end resection through CtIP deacetylation

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SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

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The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

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Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity

21 January 2018

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Developmental regulation of the growth plate

21 January 2018

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Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein

21 January 2018

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The world according to hedgehog

21 January 2018

1 reference

Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy

21 January 2018

1 reference

Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP

21 January 2018

1 reference

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

21 January 2018

1 reference

Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

21 January 2018

1 reference

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis

21 January 2018

1 reference

delta-EF1 is a negative regulator of Ihh in the developing growth plate

21 January 2018

1 reference

Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription.

21 January 2018

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Homocysteine accelerates endothelial cell senescence.

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Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

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IGF-I is required for normal embryonic growth in mice

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Insulin-like growth factor-I is essential for embryonic bone development

21 January 2018

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IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway

21 January 2018

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Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells.

21 January 2018

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TGFbeta and PTHrP control chondrocyte proliferation by activating cyclin D1 expression.

21 January 2018

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SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair

21 January 2018

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Shh controls epithelial proliferation via independent pathways that converge on N-Myc

21 January 2018

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Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation

21 January 2018

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Purmorphamine activates the Hedgehog pathway by targeting Smoothened.

21 January 2018

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Salubrinal promotes healing of surgical wounds in rat femurs.

21 January 2018

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Evidence for a negative Pasteur effect in articular cartilage

21 January 2018

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SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence

21 January 2018

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The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells

21 January 2018

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Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence

21 January 2018

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Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor

21 January 2018

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Primary culture and phenotyping of murine chondrocytes.

21 January 2018

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A new mathematical model for relative quantification in real-time RT-PCR

21 January 2018

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Transplantation of epiphyseal plate allografts between animals of different ages

21 January 2018

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12 December 2020

Igf1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy.

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12 December 2020

Ihh enhances differentiation of CFK-2 chondrocytic cells and antagonizes PTHrP-mediated activation of PKA

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12 December 2020

Basic cell metabolism of articular cartilage. Manometric studies

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12 December 2020

Physiological mechanisms adopted by chondrocytes in regulating longitudinal bone growth in rats

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12 December 2020

Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth

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12 December 2020

Cell kinetics of growth cartilage in the rat tibia. II. Measurements during ageing

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP03022

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30 June 2019

PMC publication ID

6505680

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30 June 2019

PubMed publication ID

24149372

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30 June 2019