(Q39080863)

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Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells

scientific article published on 30 October 2013

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Europe PubMed Central

PubMed publication ID

8 September 2017

Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

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microglial inhibitor

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inferred from title

Urtė Neniškytė

2

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Europe PubMed Central

PubMed publication ID

8 September 2017

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Guy C Brown

3

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author name string

Tamara C Hornik

1

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Europe PubMed Central

PubMed publication ID

8 September 2017

language of work or name

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publication date

30 October 2013

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Europe PubMed Central

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8 September 2017

Journal of Neurochemistry

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8 September 2017

128

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Europe PubMed Central

PubMed publication ID

8 September 2017

5

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Europe PubMed Central

PubMed publication ID

8 September 2017

650-661

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Europe PubMed Central

PubMed publication ID

8 September 2017

Rb-dependent cellular senescence, multinucleation and susceptibility to oncogenic transformation through PKC scaffolding by SSeCKS/AKAP12

1 reference

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Foreign body reaction to biomaterials

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Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus

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21 January 2018

An immortalized cell line expresses properties of activated microglial cells

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A two-colour fluorescence assay for the measurement of syncytial fusion between trophoblast-derived cell lines.

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Eaten alive! Cell death by primary phagocytosis: 'phagoptosis'.

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21 January 2018

Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene

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21 January 2018

Endomitotic megakaryocytes that form a bipolar spindle exhibit cleavage furrow ingression followed by furrow regression

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21 January 2018

Neuroinflammatory responses from microglia recovered from HIV-1-infected and seronegative subjects

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21 January 2018

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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21 January 2018

Age related changes in microglial phenotype vary between CNS regions: grey versus white matter differences

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21 January 2018

Molecular mediators of macrophage fusion

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21 January 2018

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

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21 January 2018

UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

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21 January 2018

Lymphokine induction of rat microglia multinucleated giant cell formation

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21 January 2018

Microglia and inflammation in Alzheimer's disease

1 reference

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21 January 2018

Multinucleated giant cell formation exhibits features of phagocytosis with participation of the endoplasmic reticulum

1 reference

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21 January 2018

Macrophage fusion and multinucleated giant cells of inflammation

1 reference

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21 January 2018

Foreign body-type multinucleated giant cell formation requires protein kinase C beta, delta, and zeta

1 reference

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21 January 2018

Amyloid beta protein activates PKC-delta and induces translocation of myristoylated alanine-rich C kinase substrate (MARCKS) in microglia

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21 January 2018

Cell death mechanisms in HIV-associated dementia: the involvement of syncytia

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21 January 2018

Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death

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21 January 2018

Understanding Cytokinesis Failure

1 reference

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21 January 2018

Microglia in neurodegenerative disease

1 reference

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21 January 2018

Role of NADPH oxidase in formation and function of multinucleated giant cells

1 reference

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21 January 2018

The regulated assembly of a PKCepsilon complex controls the completion of cytokinesis

1 reference

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21 January 2018

Making the final cut - mechanisms mediating the abscission step of cytokinesis.

1 reference

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21 January 2018

Distinct signaling pathways for induction of type II NOS by IFNgamma and LPS in BV-2 microglial cells.

1 reference

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21 January 2018

Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.

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21 January 2018

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

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21 January 2018

Inhibition of microglia multinucleated giant cell formation and induction of differentiation by GM-CSF using a porcine in vitro model

1 reference

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21 January 2018

Macrophage fusion: molecular mechanisms

1 reference

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21 January 2018

Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells

1 reference

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21 January 2018

TPA-induced multinucleation of a mesenchymal stem cell-like clone is mediated primarily by karyokinesis without cytokinesis, although cell-cell fusion also occurs

1 reference

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21 January 2018

Molecular and cellular mechanisms of mammalian cell fusion

1 reference

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21 January 2018

Identifiers

10.1111/JNC.12477

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

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