(Q39102535)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23992566%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells (English)

1 reference

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8 March 2020

1 reference

1 reference

2

1 reference

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8 March 2020

Norihito Shibata

5

1 reference

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8 March 2020

4

Nobumichi Ohoka

1 reference

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8 March 2020

3

Takayuki Hattori

1 reference

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8 March 2020

9

Mikihiko Naito

1 reference

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8 March 2020

author name string

Keiichiro Okuhira

1

1 reference

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8 March 2020

Tomoko Nishimaki-Mogami

6

1 reference

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8 March 2020

Haruhiro Okuda

7

1 reference

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8 March 2020

Masaaki Kurihara

8

1 reference

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8 March 2020

publication date

11 October 2013

1 reference

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8 March 2020

1 reference

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8 March 2020

volume

104

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8 March 2020

page(s)

1492-1498

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8 March 2020

issue

11

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8 March 2020

cites work

Global cancer statistics

1 reference

Immunohistochemistry of estrogen and progesterone receptors reconsidered: experience with 5,993 breast cancers

21 January 2018

1 reference

Coregulators in nuclear estrogen receptor action: from concept to therapeutic targeting

21 January 2018

1 reference

Molecular basis of agonism and antagonism in the oestrogen receptor

21 January 2018

1 reference

Tamoxifen therapy for breast cancer and endometrial cancer risk.

21 January 2018

1 reference

Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen.

21 January 2018

1 reference

Mechanisms of tamoxifen resistance

21 January 2018

1 reference

Plasma membrane estrogen receptors

21 January 2018

1 reference

A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling

21 January 2018

1 reference

Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein.

21 January 2018

1 reference

Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins.

21 January 2018

1 reference

Development of target protein-selective degradation inducer for protein knockdown.

21 January 2018

1 reference

Design, synthesis and biological evaluation of nuclear receptor-degradation inducers.

21 January 2018

1 reference

Double protein knockdown of cIAP1 and CRABP-II using a hybrid molecule consisting of ATRA and IAPs antagonist.

21 January 2018

1 reference

Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy.

21 January 2018

1 reference

Small molecules destabilize cIAP1 by activating auto-ubiquitylation

21 January 2018

1 reference

Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus

21 January 2018

1 reference

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

21 January 2018

1 reference

Necrotic death as a cell fate

21 January 2018

1 reference

Effects of Cu/Zn superoxide dismutase on estrogen responsiveness and oxidative stress in human breast cancer cells

21 January 2018

1 reference

Integrating clinical pharmacology concepts in individualized therapy with tyrosine kinase inhibitors

21 January 2018

1 reference

EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors.

21 January 2018

1 reference

Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers

21 January 2018

1 reference

In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants

21 January 2018

1 reference

CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/CAS.12272

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23992566%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

0 references

1 reference

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