(Q39104155)

9 September 2017

title

Myeloid-derived suppressor cell function is reduced by Withaferin A, a potent and abundant component of Withania somnifera root extract (English)

1 reference

9 September 2017

Withania somnifera

1 reference

0 references

Pratima Sinha

1

1 reference

9 September 2017

Suzanne Ostrand-Rosenberg

series ordinal

2

1 reference

9 September 2017

publication date

27 August 2013

1 reference

Cancer Immunology, Immunotherapy

9 September 2017

published in

1 reference

9 September 2017

volume

62

1 reference

9 September 2017

issue

11

1 reference

9 September 2017

page(s)

1663-1673

1 reference

Myeloid-Derived Suppressor Cells in Human Cancer

9 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Blockade of myeloid-derived suppressor cells after induction of lymphopenia improves adoptive T cell therapy in a murine model of melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Roots of Withania somnifera Inhibit Forestomach and Skin Carcinogenesis in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Chemotherapeutic efficacy of paclitaxel in combination with Withania somnifera on benzo(a)pyrene-induced experimental lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Effect of Withania somnifera on B16F-10 melanoma induced metastasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Induction of apoptosis by withaferin A in human leukemia U937 cells through down-regulation of Akt phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Effect of Withania somnifera on DMBA induced carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NF-kappaB) activation and NF-kappaB-regulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Actin microfilament aggregation induced by withaferin A is mediated by annexin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A is a potent inhibitor of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasL

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Myeloid-derived suppressor cells: linking inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Myeloid-derived suppressor cells as regulators of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A inhibits JAK/STAT3 signaling and induces apoptosis of human renal carcinoma Caki cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Simultaneous inhibition of the constitutively activated nuclear factor kappaB and of the interleukin-6 pathways is necessary and sufficient to completely overcome apoptosis resistance of human U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A down-regulates lipopolysaccharide-induced cyclooxygenase-2 expression and PGE2 production through the inhibition of STAT1/3 activation in microglial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

NF-kappaB in cancer: from innocent bystander to major culprit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

NF-kappaB: linking inflammation and immunity to cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

NF-κB and the link between inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Withaferin A inhibits tumor necrosis factor-alpha-induced expression of cell adhesion molecules by inactivation of Akt and NF-kappaB in human pulmonary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Interleukin-10 and the immune response against cancer: a counterpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Interleukin-10 ablation promotes tumor development, growth, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Macrophages regulate the angiogenic switch in a mouse model of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Macrophages are an abundant component of myeloma microenvironment and protect myeloma cells from chemotherapy drug-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Coordinated regulation of myeloid cells by tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-013-1470-2

10.1007/S00262-013-1470-2

21 January 2018

Identifiers

DOI

1 reference

9 September 2017

1 reference