(Q39115912)

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STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.

scientific article published on 5 August 2013

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scholarly article

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6 March 2020

STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas (English)

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6 March 2020

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based on heuristic

inferred from title

esophageal squamous cell carcinoma

1 reference

based on heuristic

inferred from title

Thomas Reinheckel

13

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6 March 2020

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6 March 2020

David S Klimstra

11

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D Klimstra

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6 March 2020

author name string

S Timme

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S Ihde

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C D Fichter

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V Waehle

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L Bogatyreva

5

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6 March 2020

K Atanasov

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I Kohler

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A Schöpflin

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H Geddert

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G Faller

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L Tang

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6 March 2020

D Hauschke

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M Boerries

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6 March 2020

M Werner

17

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S Lassmann

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5 August 2013

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6 March 2020

3256-3266

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6 March 2020

https://scigraph.springernature.com/pub.10.1038/onc.2013.298

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Getting the message across, STAT! Design principles of a molecular signaling circuit.

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Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.

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Targeting the interleukin-6/Jak/stat pathway in human malignancies

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Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer

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Correlation of activated STAT3 expression with clinicopathologic features in lung adenocarcinoma and squamous cell carcinoma

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Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes.

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21 January 2018

Expression of activated signal transducer and activator of transcription 3 predicts expression of vascular endothelial growth factor in and angiogenic phenotype of human gastric cancer

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21 January 2018

Expression of activated signal transducer and activator of transcription 3 predicts poor clinical outcome in gastric adenocarcinoma

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STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation

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STAT3 expression, molecular features, inflammation patterns, and prognosis in a database of 724 colorectal cancers

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A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro

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Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth

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A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB.

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Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.

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Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma

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Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src.

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Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth

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Oesophageal carcinoma

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EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes

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Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus.

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Cancer-related inflammation and Barrett's carcinogenesis: interleukin-6 and STAT3 mediate apoptotic resistance in transformed Barrett's cells

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21 January 2018

Reciprocal activation between PLK1 and Stat3 contributes to survival and proliferation of esophageal cancer cells

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21 January 2018

beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma.

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Specialized roles for cysteine cathepsins in health and disease.

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Stat3 controls lysosomal-mediated cell death in vivo.

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Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.

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Occurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cells

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Occurrence of Aurora A positive multipolar mitoses in distinct molecular classes of colorectal carcinomas and effect of Aurora A inhibition.

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GAGE: generally applicable gene set enrichment for pathway analysis

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Collagen triple helix repeat containing-1 promotes pancreatic cancer progression by regulating migration and adhesion of tumor cells

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Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

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Shroom2 regulates contractility to control endothelial morphogenesis

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Effects of ANGPTL3 antisense oligodeoxynucleotides transfection on the cell growths and invasion of human hepatocellular carcinoma cells.

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Association of HER2/ErbB2 expression and gene amplification with pathologic features and prognosis in esophageal adenocarcinomas

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Toxin-induced RhoA activity mediates CCL1-triggered signal transducers and activators of transcription protein signaling

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Methylation of SOCS-3 and SOCS-1 in the carcinogenesis of Barrett's adenocarcinoma

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Aurora A is differentially expressed and regulated in chromosomal and microsatellite instable sporadic colorectal cancers.

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Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks

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Preface: STAT signaling

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Stat proteins and oncogenesis

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EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus

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Significance of HER2 Low-Level Copy Gain in Barrett's Cancer: Implications for Fluorescence In situ Hybridization Testing in Tissues

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Expression of anaplastic lymphoma kinase, tyrosine-phosphorylated STAT3, and associated factors in pediatric anaplastic large cell lymphoma: A report from the children's oncology group

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