(Q39129548)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25219681%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Variants of the melanocortin-1 receptor: do they matter clinically? (English)

1 reference

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16 February 2020

2

1 reference

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16 February 2020

Eugene Healy

series ordinal

4

1 reference

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16 February 2020

author name string

Ciara Haddadeen

series ordinal

1

1 reference

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16 February 2020

Shin-Young Cho

series ordinal

3

1 reference

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16 February 2020

language of work or name

1 reference

11 November 2014

1 reference

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16 February 2020

published in

Experimental Dermatology

1 reference

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16 February 2020

volume

24

1 reference

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16 February 2020

issue

1

1 reference

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16 February 2020

page(s)

5-9

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Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: a comparative review

16 February 2020

cites work

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Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation

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A polymorphism in the agouti signaling protein gene is associated with human pigmentation

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Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

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SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans

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Genetic determinants of hair, eye and skin pigmentation in Europeans

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Melanocortin 1 receptor mutations impact differentially on signalling to the cAMP and the ERK mitogen-activated protein kinase pathways

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Human melanocortin 1 receptor (MC1R) gene variants alter melanoma cell growth and adhesion to extracellular matrix

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Protection against UVR involves MC1R-mediated non-pigmentary and pigmentary mechanisms in vivo

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Functional variation of MC1R alleles from red-haired individuals.

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Quantitative measures of the effect of the melanocortin 1 receptor on human pigmentary status

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Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation

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Two newly identified genetic determinants of pigmentation in Europeans

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Diversity of human hair pigmentation as studied by chemical analysis of eumelanin and pheomelanin

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Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis

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A possible link between neural tube defects and ultraviolet light exposure

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Evidence for variable selective pressures at MC1R

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The evolution of human skin coloration

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Simultaneous purifying selection on the ancestral MC1R allele and positive selection on the melanoma-risk allele V60L in south Europeans

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PIGMENTATION, SUNLIGHT, AND NUTRITIONAL DISEASE

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Vitamin D: in the evolution of human skin colour

21 January 2018

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Birthweight and perinatal mortality: II. On weight-specific mortality

21 January 2018

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Melanocortin 1 receptor variants in an Irish population

21 January 2018

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Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair

21 January 2018

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Melanocortin-1 receptor genotype is a risk factor for basal and squamous cell carcinoma

21 January 2018

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Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype?

21 January 2018

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ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma

21 January 2018

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Host phenotype characteristics and MC1R in relation to early-onset basal cell carcinoma

21 January 2018

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MC1R genotype as a predictor of early-onset melanoma, compared with self-reported and physician-measured traditional risk factors: an Australian case-control-family study

21 January 2018

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Cutaneous expression of corticotropin-releasing hormone (CRH), urocortin, and CRH receptors

21 January 2018

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Solar-simulated ultraviolet radiation-induced upregulation of the melanocortin-1 receptor, proopiomelanocortin, and alpha-melanocyte-stimulating hormone in human epidermis in vivo

21 January 2018

1 reference

alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage

21 January 2018

1 reference

alpha-MSH tripeptide analogs activate the melanocortin 1 receptor and reduce UV-induced DNA damage in human melanocytes

21 January 2018

1 reference

Functional melanocortin 1 receptor Mc1r is not necessary for an inflammatory response to UV radiation in adult mouse skin

21 January 2018

1 reference

Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation

21 January 2018

1 reference

Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.

21 January 2018

1 reference

alpha-MSH activates immediate defense responses to UV-induced oxidative stress in human melanocytes

21 January 2018

1 reference

Alpha-melanocyte-stimulating hormone counteracts the suppressive effect of UVB on Nrf2 and Nrf-dependent gene expression in human skin

21 January 2018

1 reference

Alpha-melanocyte-stimulating hormone suppresses oxidative stress through a p53-mediated signaling pathway in human melanocytes.

21 January 2018

1 reference

MC1R expression in HaCaT keratinocytes inhibits UVA-induced ROS production via NADPH oxidase- and cAMP-dependent mechanisms

21 January 2018

1 reference

CYLD inhibits melanoma growth and progression through suppression of the JNK/AP-1 and β1-integrin signaling pathways

21 January 2018

1 reference

MC1R is a potent regulator of PTEN after UV exposure in melanocytes

21 January 2018

1 reference

Immunoreactive alpha-melanotropin as an autocrine effector in human melanoma cells

21 January 2018

1 reference

alpha-Melanotropin immunoreactivity in human melanoma exudate is related to necrosis.

21 January 2018

1 reference

Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor

21 January 2018

1 reference

Alpha-melanocyte-stimulating hormone suppresses antigen-induced lymphocyte proliferation in humans independently of melanocortin 1 receptor gene status

21 January 2018

1 reference

The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humans

21 January 2018

1 reference

Inherited variants in the MC1R gene and survival from cutaneous melanoma: a BioGenoMEL study

21 January 2018

1 reference

Is MC1 dispensable for regulation of cutaneous inflammatory and immune responses?

21 January 2018

1 reference

Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi

21 January 2018

1 reference

Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma

21 January 2018

1 reference

Interactive effects of MC1R and OCA2 on melanoma risk phenotypes

21 January 2018

1 reference

"White" nevi and "red" melanomas: association with the RHC phenotype of the MC1R gene

21 January 2018

1 reference

CDKN2A and MC1R variants influence dermoscopic and confocal features of benign melanocytic lesions in multiple melanoma patients.

21 January 2018

1 reference

Melanocortin 1 receptor (MC1R) variants in high melanoma risk patients are associated with specific dermoscopic ABCD features

21 January 2018

1 reference

Germline melanocortin-1-receptor genotype is associated with severity of cutaneous phenotype in congenital melanocytic nevi: a role for MC1R in human fetal development

21 January 2018

1 reference

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

21 January 2018

1 reference

Genome-wide association study identifies three new melanoma susceptibility loci

21 January 2018

1 reference

Association of MC1R variants and host phenotypes with melanoma risk in CDKN2A mutation carriers: a GenoMEL study

21 January 2018

1 reference

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

21 January 2018

1 reference

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.

21 January 2018

1 reference

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

21 January 2018

1 reference

MC1R variants increase risk of melanomas harboring BRAF mutations.

21 January 2018

1 reference

The association between MC1R genotype and BRAF mutation status in cutaneous melanoma: findings from an Australian population

21 January 2018

1 reference

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

21 January 2018

1 reference

Site distribution of cutaneous melanoma in Queensland

21 January 2018

1 reference

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo

21 January 2018

1 reference

Vitiligo: interplay between oxidative stress and immune system

21 January 2018

1 reference

Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling.

21 January 2018

1 reference

The efficacy of afamelanotide and narrowband UV-B phototherapy for repigmentation of vitiligo

21 January 2018

1 reference

[Nle4-D-Phe7]-alpha-melanocyte-stimulating hormone significantly increased pigmentation and decreased UV damage in fair-skinned Caucasian volunteers

21 January 2018

1 reference

Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning

21 January 2018

1 reference

Change in moles linked to use of unlicensed "sun tan jab"

21 January 2018

1 reference

alpha-Melanocyte-stimulating hormone-induced eruptive nevi

21 January 2018

1 reference

Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial

21 January 2018

1 reference

Reduced melanoma after regular sunscreen use: randomized trial follow-up

21 January 2018

1 reference

The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma

21 January 2018

1 reference

Functional MC1R-Gene Variants Are Associated with Increased Risk for Severe Photoaging of Facial Skin

21 January 2018

1 reference

NRAS and BRAF Mutations in Cutaneous Melanoma and the Association with MC1R Genotype: Findings from Spanish and Austrian Populations

21 January 2018

1 reference

Melanocortin 1 Receptor (MC1R) Gene Variants are Associated with an Increased Risk for Cutaneous Melanoma Which is Largely Independent of Skin Type and Hair Color

21 January 2018

1 reference