(Q39135703)

English

Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G.

scientific article published on 28 October 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G. (English)

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Bianca Altvater

object named as

Bianca Altvater

2

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Wolfgang Hartmann

object named as

Wolfgang Hartmann

10

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object named as

Heinz Wiendl

11

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author name string

Sareetha Kailayangiri

1

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Europe PubMed Central

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2 November 2017

Christian Spurny

3

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2 November 2017

Silke Jamitzky

4

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Europe PubMed Central

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2 November 2017

Sonja Schelhaas

5

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Europe PubMed Central

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2 November 2017

Andreas H Jacobs

6

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Europe PubMed Central

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2 November 2017

Constanze Wiek

7

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Europe PubMed Central

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2 November 2017

Katharina Roellecke

8

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Europe PubMed Central

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2 November 2017

Helmut Hanenberg

9

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Europe PubMed Central

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2 November 2017

Susann Pankratz

12

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Europe PubMed Central

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2 November 2017

Jutta Meltzer

13

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Europe PubMed Central

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2 November 2017

Nicole Farwick

14

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Europe PubMed Central

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2 November 2017

Lea Greune

15

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Europe PubMed Central

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2 November 2017

Maike Fluegge

16

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Europe PubMed Central

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2 November 2017

Claudia Rossig

17

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Europe PubMed Central

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2 November 2017

publication date

28 October 2016

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Europe PubMed Central

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2 November 2017

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Europe PubMed Central

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2 November 2017

6

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Europe PubMed Central

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2 November 2017

1

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Europe PubMed Central

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2 November 2017

e1250050

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Effective combination treatment of GD2-expressing neuroblastoma and Ewing's sarcoma using anti-GD2 ch14.18/CHO antibody with Vγ9Vδ2+ γδT cells

1 reference

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1 reference

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DAP12-based activating chimeric antigen receptor for NK cell tumor immunotherapy

1 reference

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1 reference

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T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

1 reference

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Chimeric antigen receptor T cells for sustained remissions in leukemia

1 reference

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Anchorage-independent growth of Ewing sarcoma cells under serum-free conditions is not associated with stem-cell like phenotype and function

1 reference

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Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors

1 reference

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CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma

1 reference

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Arming cytokine-induced killer cells with chimeric antigen receptors: CD28 outperforms combined CD28-OX40 "super-stimulation".

1 reference

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Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells

1 reference

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Cytokine activation induces human memory-like NK cells

1 reference

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15 June 2018

Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

Cytotoxicity of activated natural killer cells against pediatric solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort

1 reference

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15 June 2018

2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

Human neuroblastoma cells trigger an immunosuppressive program in monocytes by stimulating soluble HLA-G release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

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Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells

1 reference

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Soluble HLA-G protein secreted by allo-specific CD4+ T cells suppresses the allo-proliferative response: a CD4+ T cell regulatory mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

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Tumor-specific up-regulation of the nonclassical class I HLA-G antigen expression in renal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283645

15 June 2018

Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production

1 reference

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HLA-G2, -G3, and -G4 isoforms expressed as nonmature cell surface glycoproteins inhibit NK and antigen-specific CTL cytolysis

1 reference

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A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells

1 reference

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HLA-G expression in melanoma: a way for tumor cells to escape from immunosurveillance

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Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis

1 reference

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Favorable NK cell activity after haploidentical hematopoietic stem cell transplantation in stage IV relapsed Ewing's sarcoma patients

1 reference

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Zoledronic acid negatively affects the expansion of in vitro activated human NK cells and their cytolytic interactions with Ewing sarcoma cells

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Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial.

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Tumor marker usage and medical care costs among older early-stage breast cancer survivors

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Surface expression of HLA-G is involved in mediating immunomodulatory effects of placenta-derived multipotent cells (PDMCs) towards natural killer lymphocytes

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haploidentical stem cell transplantation in patients with pediatric solid tumors: preliminary results of a pilot study and analysis of graft versus tumor effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/28197367

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple method for identifying bone marrow mesenchymal stromal cells with a high immunosuppressive potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/28197367

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/2162402X.2016.1250050

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

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