(Q39144862)

9 September 2017

A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer (English)

1 reference

Author Correction: A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer

9 September 2017

1 reference

corrigendum / erratum

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13

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9 September 2017

21

Pier Paolo Pandolfi

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John G Clohessy

John G Clohessy

5

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Leonardo Salmena

Leonardo Salmena

4

0 references

Maristella Bianconi

Maristella Bianconi

9

0 references

Ugo Ala

Ugo Ala

2

0 references

Carlos Cordon-Cardo

15

Carlos Cordon-Cardo

1 reference

9 September 2017

19

Massimo Loda

1 reference

9 September 2017

17

Rodolfo Montironi

1 reference

9 September 2017

18

Sabina Signoretti

1 reference

9 September 2017

20

Caterina Nardella

1 reference

9 September 2017

1

Andrea Lunardi

1 reference

9 September 2017

6

Kaitlyn A Webster

1 reference

9 September 2017

3

Mirjam T Epping

1 reference

9 September 2017

12

Akash Patnaik

1 reference

9 September 2017

Guocan Wang

7

1 reference

9 September 2017

Roberta Mazzucchelli

8

1 reference

9 September 2017

Edward C Stack

10

1 reference

9 September 2017

Rosina Lis

11

1 reference

9 September 2017

Glenn Bubley

14

1 reference

9 September 2017

William L Gerald

16

1 reference

9 September 2017

language of work or name

English

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publication date

2 June 2013

1 reference

9 September 2017

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9 September 2017

45

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9 September 2017

7

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9 September 2017

747-755

1 reference

describes a project that uses

9 September 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3787876

inferred from PubMed Central ID database lookup

cites work

Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Targeting X-linked inhibitor of apoptosis protein inhibits pancreatic cancer cell growth through p-Akt depletion

10 September 2017

1 reference

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The mutational landscape of lethal castration-resistant prostate cancer

10 September 2017

1 reference

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POK/ZBTB proteins: an emerging family of proteins that regulate lymphoid development and function

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Molecular classification of prostate cancer using curated expression signatures

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

The APL paradigm and the "co-clinical trial" project

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Natural IAP inhibitor Embelin enhances therapeutic efficacy of ionizing radiation in prostate cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Novel therapeutic strategies for castration resistant prostate cancer: inhibition of persistent androgen production and androgen receptor mediated signaling

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Overcoming persistent dependency on androgen signaling after progression to castration-resistant prostate cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Integrative genomic profiling of human prostate cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Dutasteride and bicalutamide in patients with hormone-refractory prostate cancer: the Therapy Assessed by Rising PSA (TARP) study rationale and design.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

IAPs: more than just inhibitors of apoptosis proteins

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

In vivo MRI volumetric measurement of prostate regression and growth in mice

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Integrative molecular concept modeling of prostate cancer progression.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Integration of gene expression profiling and clinical variables to predict prostate carcinoma recurrence after radical prostatectomy

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

The patient with hormone-refractory prostate cancer: determining who, when, and how to treat

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Pten dose dictates cancer progression in the prostate

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Molecular biology of the androgen receptor

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Proliferation- and apoptosis-associated factors in advanced prostatic carcinomas before and after androgen deprivation therapy: prognostic significance of p21/WAF1/CIP1 expression

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Combination therapy of antiandrogen and XIAP inhibitor for treating advanced prostate cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

XIAP-associated factor 1 (XAF1), a novel target of p53, enhances p53-mediated apoptosis via post-translational modification

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein inhibits colon cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Gene expression analysis of prostate cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Management of cancer of the prostate

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Characterizing the Contribution of Stem/Progenitor Cells to Tumorigenesis in thePten−/−TP53−/− Prostate Cancer Model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

XAF1 as a prognostic biomarker and therapeutic target in pancreatic cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Activity of dutasteride plus ketoconazole in castration-refractory prostate cancer after progression on ketoconazole alone

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Gene expression profile in colon cancer cells with respect to XIAP expression status.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787876

Clinical significance of p53 alterations in surgically treated prostate cancers

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23727860

12 December 2020

inferred from PubMed ID database lookup

Role of PTEN gene in progression of prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23727860

12 December 2020

inferred from PubMed ID database lookup

Neoadjuvant Therapy for Prostate Cancer: An Oncologist's Perspective

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23727860

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NG.2650

1 reference

Dimensions Publication ID

9 September 2017

0 references

1 reference

9 September 2017

PubMed publication ID

23727860

1 reference