(Q39145011)

English

An atrial-fibrillation-linked connexin40 mutant is retained in the endoplasmic reticulum and impairs the function of atrial gap-junction channels

scientific article published on 13 March 2014

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

An atrial-fibrillation-linked connexin40 mutant is retained in the endoplasmic reticulum and impairs the function of atrial gap-junction channels (English)

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

endoplasmic reticulum

0 references

atrial fibrillation

0 references

8

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

object named as

Dale W Laird

7

0 references

author name string

Yiguo Sun

1

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Xiaoling Tong

2

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Honghong Chen

3

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Tao Huang

4

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Qing Shao

5

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Weixiong Huang

6

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

publication date

13 March 2014

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Disease Models & Mechanisms

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

561-569

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

copyright license

Creative Commons Attribution 3.0 Unported

18 May 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Channeling diversity: gap junction expression in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Atrial fibrillation: current knowledge and future directions in epidemiology and genomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

The genetics of atrial fibrillation: from the bench to the bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Paradigm of genetic mosaicism and lone atrial fibrillation: physiological characterization of a connexin 43-deletion mutant identified from atrial tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Genome-wide association study of PR interval

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Cardiac connexins and impulse propagation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Execution of nonsense-mediated mRNA decay: what defines a substrate?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Atrial natriuretic peptide frameshift mutation in familial atrial fibrillation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Connexin40 imparts conduction heterogeneity to atrial tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Remodelling of gap junctions and connexin expression in diseased myocardium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Is there a role for remodeled connexins in AF? No simple answers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Genes and atrial fibrillation: a new look at an old problem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Mechanism of origin of conduction disturbances in aging human atrial bundles: experimental and model study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Altered right atrial excitation and propagation in connexin40 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

ERAD: the long road to destruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Genomic organization and alternative transcripts of the human Connexin40 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

KCNQ1 gain-of-function mutation in familial atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Dislocation and degradation from the ER are regulated by cytosolic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Gap junction channels formed by coexpressed connexin40 and connexin43

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Chamber-related differences in connexin expression in the human heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

10 September 2017

The role of amino terminus of mouse Cx50 in determining transjunctional voltage-dependent gating and unitary conductance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

14 September 2017

Connexin40 and connexin43 determine gating properties of atrial gap junction channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

14 September 2017

N-terminal residues in Cx43 and Cx40 determine physiological properties of gap junction channels, but do not influence heteromeric assembly with each other or with Cx26.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

14 September 2017

Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

14 September 2017

Cx40 and Cx43 expression ratio influences heteromeric/ heterotypic gap junction channel properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

25 September 2017

Identification of a genetic locus for familial atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

25 September 2017

Gap junction protein phenotypes of the human heart and conduction system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

25 September 2017

Conduction disturbances and increased atrial vulnerability in Connexin40-deficient mice analyzed by transesophageal stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

15 June 2018

Restricted distribution of connexin40, a gap junctional protein, in mammalian heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

15 June 2018

Rare variants in GJA5 are associated with early-onset lone atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

21 August 2018

Novel connexin40 missense mutations in patients with familial atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

21 August 2018

Dominant arrhythmia vulnerability of the right ventricle in senescent mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

21 August 2018

Relative contributions of connexins 40 and 43 to atrial impulse propagation in synthetic strands of neonatal and fetal murine cardiomyocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

21 August 2018

Specific amino-acid residues in the N-terminus and TM3 implicated in channel function and oligomerization compatibility of connexin43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007407

21 August 2018

The association of human connexin 40 genetic polymorphisms with atrial fibrillation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24626989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetics of atrial fibrillation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24626989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative expression of immunolocalized connexins 40 and 43 correlates with human atrial conduction properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/24626989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural correlate of atrial fibrillation in human patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24626989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons

1 reference

https://pubmed.ncbi.nlm.nih.gov/24626989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of human connexin40 gene polymorphisms with atrial vulnerability as a risk factor for idiopathic atrial fibrillation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24626989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Connexin40 nonsense mutation in familial atrial fibrillation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24626989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atrial fibrillation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24626989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1242/DMM.013813

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39145011&oldid=1862361418"