(Q39146191)

English

The proteasome inhibitor bortezomib is a potent inducer of zinc finger AN1-type domain 2a gene expression: role of heat shock factor 1 (HSF1)-heat shock factor 2 (HSF2) heterocomplexes

scientific article published on 11 March 2014

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PMC publication ID

9 September 2017

The proteasome inhibitor bortezomib is a potent inducer of zinc finger AN1-type domain 2a gene expression: role of heat shock factor 1 (HSF1)-heat shock factor 2 (HSF2) heterocomplexes (English)

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9 September 2017

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9 June 2020

Simone La Frazia

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9 June 2020

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Antonio Rossi

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9 June 2020

Marta Coccia

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9 June 2020

Edoardo Trotta

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9 June 2020

M Gabriella Santoro

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9 June 2020

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11 March 2014

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9 September 2017

Journal of Biological Chemistry

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9 June 2020

289

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9 June 2020

18

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9 June 2020

12705-12715

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9 June 2020

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Molecular architecture and assembly of the eukaryotic proteasome

1 reference

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10 September 2017

The ubiquitin proteasome system - implications for cell cycle control and the targeted treatment of cancer

1 reference

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10 September 2017

Development of proteasome inhibitors as research tools and cancer drugs

1 reference

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10 September 2017

Covalent and non-covalent reversible proteasome inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Post-translational modification of human heat shock factors and their functions: a recent update by proteomic approach

1 reference

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10 September 2017

The ubiquitin-proteasome system meets angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Regulation of hematopoietic stem cell fate by the ubiquitin proteasome system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Regulation of cyclooxygenase-2 expression by heat: a novel aspect of heat shock factor 1 function in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Proteasome inhibitors and modulators of angiogenesis in multiple myeloma

1 reference

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10 September 2017

Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

1 reference

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10 September 2017

p21(WAF1/CIP1) upregulation through the stress granule-associated protein CUGBP1 confers resistance to bortezomib-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Regulation of HSF1 function in the heat stress response: implications in aging and disease

1 reference

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10 September 2017

Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives

1 reference

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10 September 2017

Heat shock factors: integrators of cell stress, development and lifespan.

1 reference

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10 September 2017

Proteasome regulators: activators and inhibitors.

1 reference

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10 September 2017

Heterotrimerization of heat-shock factors 1 and 2 provides a transcriptional switch in response to distinct stimuli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans

1 reference

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10 September 2017

Inhibition of the ubiquitin-proteasome system induces stress granule formation.

1 reference

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10 September 2017

Role of ubiquitin- and Ubl-binding proteins in cell signaling

1 reference

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10 September 2017

An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity

1 reference

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10 September 2017

A phase I and pharmacologic trial of two schedules of the proteasome inhibitor, PS-341 (bortezomib, velcade), in patients with advanced cancer

1 reference

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10 September 2017

Pharmacology, pharmacokinetics, and practical applications of bortezomib

1 reference

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10 September 2017

Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Determination of the consensus binding sequence for the purified embryonic heat shock factor 2.

1 reference

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10 September 2017

Arsenite-inducible RNA-associated protein (AIRAP) protects cells from arsenite toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Roles of the heat shock transcription factors in regulation of the heat shock response and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Heat shock factor 2 is activated during mouse heart development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Induction of ferritin and heat shock proteins by prostaglandin A1 in human monocytes. Evidence for transcriptional and post-transcriptional regulation

1 reference

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10 September 2017

Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators

1 reference

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10 September 2017

The ubiquitin system

1 reference

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10 September 2017

Inhibition of nuclear factor kappa B by prostaglandin A1: an effect associated with heat shock transcription factor activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007460

10 September 2017

Characterization of constitutive HSF2 DNA-binding activity in mouse embryonal carcinoma cells

1 reference

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10 September 2017

Selection of new HSF1 and HSF2 DNA-binding sites reveals difference in trimer cooperativity

1 reference

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10 September 2017

Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells

1 reference

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10 September 2017

Stress-specific activation and repression of heat shock factors 1 and 2.

1 reference

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10 September 2017

Heat shock response and protein degradation: regulation of HSF2 by the ubiquitin-proteasome pathway

1 reference

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14 September 2017

AIRAP, a new human heat shock gene regulated by heat shock factor 1.

1 reference

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14 September 2017

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib

1 reference

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14 September 2017

Up-regulation of the clusterin gene after proteotoxic stress: implication of HSF1-HSF2 heterocomplexes.

1 reference

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14 September 2017

Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance

1 reference

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25 September 2017

Anaphase-promoting complex/cyclosome participates in the acute response to protein-damaging stress

1 reference

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25 September 2017

Concomitant determination of absolute values of cellular protein amounts, synthesis rates, and turnover rates by quantitative proteome profiling.

1 reference

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15 June 2018

Attenuation of the heat shock response in HeLa cells is mediated by the release of bound heat shock transcription factor and is modulated by changes in growth and in heat shock temperatures

1 reference

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15 June 2018

Bortezomib induces autophagic death in proliferating human endothelial cells.

1 reference

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21 August 2018

Hsp70 is required for optimal cell proliferation in mouse A6 mesoangioblast stem cells

1 reference

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21 August 2018

Differential recognition of heat shock elements by members of the heat shock transcription factor family.

1 reference

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21 August 2018

Targeting the heat shock factor 1 by RNA interference: a potent tool to enhance hyperthermochemotherapy efficacy in cervical cancer.

1 reference

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21 August 2018

Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells

1 reference

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21 August 2018

Differentiation lineage-specific expression of human heat shock transcription factor 2.

1 reference

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21 August 2018

Activation of the heat shock factor 1 by serine protease inhibitors. An effect associated with nuclear factor-kappaB inhibition

1 reference

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21 August 2018

Proteasome inhibition leads to the activation of all members of the heat-shock-factor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/24619424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat Shock Factor 2 (HSF2) Contributes to Inducible Expression ofhspGenes through Interplay with HSF1

1 reference

https://pubmed.ncbi.nlm.nih.gov/24619424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible transcription factor-1 alpha determines sensitivity of endothelial cells to the proteosome inhibitor bortezomib

1 reference

https://pubmed.ncbi.nlm.nih.gov/24619424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of heat shock factor 1 and 2 in response to proteasome inhibition: consequence on p53 stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/24619424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.513242

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619424%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619424%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619424%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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