(Q39152114)

9 September 2017

1 reference

5 July 2021

The Heterocellular Emergence of Colorectal Cancer (English)

1 reference

9 September 2017

1 reference

5 July 2021

genetic heterogeneity

1 reference

25 January 2021

1 reference

5 July 2021

1 reference

PubMed publication ID

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28239669%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Christopher J Tape

series ordinal

1

1 reference

9 September 2017

language of work or name

1 reference

1 February 2017

7 references

9 September 2017

21 March 2019

3 April 2019

30 June 2019

14 September 2019

25 January 2021

5 July 2021

7 references

21 March 2019

3 April 2019

30 June 2019

14 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28239669%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

25 January 2021

5 July 2021

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28239669%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28239669%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

79-88

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28239669%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 June 2020

copyright license

6 references

21 March 2019

3 April 2019

30 June 2019

14 September 2019

25 January 2021

on focus list of Wikimedia project

5 July 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

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Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation

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IL-33 activates tumor stroma to promote intestinal polyposis.

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A Big Bang model of human colorectal tumor growth

10 September 2017

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Proteomics. Tissue-based map of the human proteome

10 September 2017

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10 September 2017

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Regional specialization within the intestinal immune system

10 September 2017

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10 September 2017

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Intestinal epithelial cells: regulators of barrier function and immune homeostasis

10 September 2017

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Hedgehog signaling controls T cell killing at the immunological synapse

10 September 2017

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10 September 2017

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10 September 2017

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Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically

10 September 2017

1 reference

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10 September 2017

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10 September 2017

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Crosstalk between colon cancer cells and macrophages via inflammatory mediators and CD47 promotes tumour cell migration

10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts

10 September 2017

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10 September 2017

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Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer

10 September 2017

1 reference

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Mesenchymal cells of the intestinal lamina propria

10 September 2017

1 reference

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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Hedgehog signaling in development and homeostasis of the gastrointestinal tract

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Organizing cell renewal in the intestine: stem cells, signals and combinatorial control

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Histological categorisation of fibrotic cancer stroma in advanced rectal cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Targeting RAS signalling pathways in cancer therapy

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

APC, signal transduction and genetic instability in colorectal cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Blockade of a chemokine, CCL2, reduces chronic colitis-associated carcinogenesis in mice.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Macrophages in human colorectal cancer are pro-inflammatory and prime T cells towards an anti-tumour type-1 inflammatory response

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Desmoplasia measured by computer assisted image analysis: an independent prognostic marker in colorectal carcinoma.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

The desmoplastic reaction surrounding hepatic colorectal adenocarcinoma metastases aids tumor growth and survival via alphav integrin ligation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Role of desmoplasia in recurrence of stage II colorectal cancer within five years after surgery and therapeutic implication

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Common effector processing mediates cell-specific responses to stimuli

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Role of cancer-associated stromal fibroblasts in metastatic colon cancer to the liver and their expression profiles

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Prognostic impact of tumour-infiltrating B cells and plasma cells in colorectal cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Human colonic myofibroblasts promote expansion of CD4+ CD25high Foxp3+ regulatory T cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

PD-1 ligand expression by human colonic myofibroblasts/fibroblasts regulates CD4+ T-cell activity

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Roles of myofibroblasts in prostaglandin E2-stimulated intestinal epithelial proliferation and angiogenesis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Expression pattern of Wnt signaling components in the adult intestine.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312168

Targeting the Microenvironment in Advanced Colorectal Cancer

21 August 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.12.004

Emergence as a Construct: History and Issues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.12.004

Colorectal Cancer Subtypes: Developmental Origin and Microenvironmental Regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.12.004

Progressive cellular response in the lamina propria of the colorectal adenoma-carcinoma sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.12.004

Stromal myofibroblasts predict disease recurrence for colorectal cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.12.004

GM-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8, IL-10, ICAM-1 and VCAM-1 gene expression and cytokine production in human duodenal fibroblasts stimulated with lipopolysaccharide, IL-1 alpha and TNF-alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.12.004

Subepithelial myofibroblasts are novel nonprofessional APCs in the human colonic mucosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.12.004

Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.12.004

CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28239669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TRECAN.2016.12.004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28239669%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28239669%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

28239669

1 reference