(Q39161035)

9 September 2017

title

Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering (English)

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9 September 2017

Kyoung Ho Lee

1

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9 September 2017

Masayoshi Onitsuka

2

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9 September 2017

Kohsuke Honda

3

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9 September 2017

Hisao Ohtake

4

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9 September 2017

Takeshi Omasa

5

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9 September 2017

language of work or name

English

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publication date

25 April 2013

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Applied Microbiology and Biotechnology

9 September 2017

published in

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9 September 2017

volume

97

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9 September 2017

issue

13

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9 September 2017

page(s)

5731-5741

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Uncoupling of cell growth and proliferation results in enhancement of productivity in p21CIP1-arrested CHO cells.

9 September 2017

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Population balance between producing and nonproducing hybridoma clones is very sensitive to serum level, state of inoculum, and medium composition

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Effect of doxycycline-regulated calnexin and calreticulin expression on specific thrombopoietin productivity of recombinant Chinese hamster ovary cells

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ATR: an essential regulator of genome integrity

21 January 2018

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Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons

21 January 2018

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21 January 2018

Chromosome fragile sites

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Amplification and expression of recombinant genes in serum-independent Chinese hamster ovary cells.

21 January 2018

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DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

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Fragile sites: overview, occurrence in acute nonlymphocytic leukemia and effects of caffeine on expression

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Effect of cDNA copy number on secretion rate of activated protein C.

21 January 2018

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21 January 2018

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Genomic sequencing and analysis of a Chinese hamster ovary cell line using Illumina sequencing technology

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Combinatorial engineering of ldh-a and bcl-2 for reducing lactate production and improving cell growth in dihydrofolate reductase-deficient Chinese hamster ovary cells

21 January 2018

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Regulation of recombinant monoclonal antibody production in chinese hamster ovary cells: a comparative study of gene copy number, mRNA level, and protein expression.

21 January 2018

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cMyc increases cell number through uncoupling of cell division from cell size in CHO cells

21 January 2018

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CHO cells in biotechnology for production of recombinant proteins: current state and further potential

21 January 2018

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Glycosylation pattern of humanized IgG-like bispecific antibody produced by recombinant CHO cells

21 January 2018

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Human chromosome fragility

21 January 2018

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Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells

21 January 2018

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E2F-1 overexpression increases viable cell density in batch cultures of Chinese hamster ovary cells

21 January 2018

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Specific chromosome instability induced by heavy ions: a step towards transformation of human fibroblasts?

21 January 2018

1 reference

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Effect of doxycycline-regulated protein disulfide isomerase expression on the specific productivity of recombinant CHO cells: thrombopoietin and antibody

21 January 2018

1 reference

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SMC1 involvement in fragile site expression.

21 January 2018

1 reference

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Application of destabilizing sequences on selection marker for improved recombinant protein productivity in CHO-DG44.

21 January 2018

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Systems biotechnology of mammalian cell factories

21 January 2018

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Improved production of recombinant human antithrombin III in Chinese hamster ovary cells by ATF4 overexpression.

21 January 2018

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Gene amplification and its application in cell and tissue engineering.

21 January 2018

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Enhancement of sialylation on humanized IgG-like bispecific antibody by overexpression of α2,6-sialyltransferase derived from Chinese hamster ovary cells.

21 January 2018

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Effect of cloned gene dosage on cell growth and hepatitis B surface antigen synthesis and secretion in recombinant CHO cells

21 January 2018

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High-level expression of human thyroid-stimulating hormone in Chinese hamster ovary cells by co-transfection of dicistronic expression vectors followed by a dual-marker amplification strategy.

21 January 2018

1 reference

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ATR (ataxia telangiectasia mutated- and Rad3-related kinase) is activated by mild hypothermia in mammalian cells and subsequently activates p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4923-9

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

21 January 2018

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Production of recombinant protein therapeutics in cultivated mammalian cells

21 January 2018

1 reference

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Expression of chimeric antibody in mammalian cells using dicistronic expression vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4923-9

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4923-9

Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4923-9

Amplified gene location in chromosomal DNA affected recombinant protein production and stability of amplified genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4923-9

Flow cytometry: an improved method for the selection of highly productive gene-amplified CHO cells using flow cytometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4923-9

10.1007/S00253-013-4923-9

21 January 2018

Identifiers

DOI

1 reference

9 September 2017

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