(Q39163743)

9 September 2017

title

24(S)-hydroxycholesterol is actively eliminated from neuronal cells by ABCA1. (English)

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9 September 2017

5

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9 September 2017

Akihiro Matsuda

1

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9 September 2017

Kohjiro Nagao

series ordinal

2

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9 September 2017

Michinori Matsuo

series ordinal

3

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9 September 2017

Noriyuki Kioka

series ordinal

4

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9 September 2017

language of work or name

English

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publication date

8 May 2013

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Journal of Neurochemistry

9 September 2017

published in

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9 September 2017

volume

126

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9 September 2017

issue

1

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9 September 2017

page(s)

93-101

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24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux.

9 September 2017

cites work

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From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans

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Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels

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Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

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Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function

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1 reference

Expression of ABCG1, but not ABCA1, correlates with cholesterol release by cerebellar astroglia

21 January 2018

1 reference

Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1

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1 reference

22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

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The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells.

21 January 2018

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Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta

21 January 2018

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Brain cholesterol turnover required for geranylgeraniol production and learning in mice

21 January 2018

1 reference

Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover

21 January 2018

1 reference

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

21 January 2018

1 reference

Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins

21 January 2018

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On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function.

21 January 2018

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Alpha1-syntrophin modulates turnover of ABCA1.

21 January 2018

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Sodium taurocholate-dependent lipid efflux by ABCA1: effects of W590S mutation on lipid translocation and apolipoprotein A-I dissociation

21 January 2018

1 reference

ATP hydrolysis-dependent conformational changes in the extracellular domain of ABCA1 are associated with apoA-I binding

21 January 2018

1 reference

Brain-to-blood elimination of 24S-hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood-brain barrier

21 January 2018

1 reference

Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes

21 January 2018

1 reference

Identification of 24-hydroxycholesterol in bovine adrenals in both free and esterified forms and in bovine brains as its sulfate ester

21 January 2018

1 reference

Screening for functional sequence variations and mutations in ABCA1.

21 January 2018

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Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

21 January 2018

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APOE is a major susceptibility gene for Alzheimer's disease

21 January 2018

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Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain

21 January 2018

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Distinct spatio-temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain.

21 January 2018

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ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells

21 January 2018

1 reference

Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjögren's Syndrome

21 January 2018

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ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2

21 January 2018

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High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1

21 January 2018

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ABC proteins protect the human body and maintain optimal health

21 January 2018

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ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins

21 January 2018

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ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

21 January 2018

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Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.

21 January 2018

1 reference

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

21 January 2018

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ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain

21 January 2018

1 reference

Differentiation of human neuroblastoma cells: marked potentiation of prostaglandin E-stimulated accumulation of cyclic AMP by retinoic acid.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/JNC.12275

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9 September 2017

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