(Q39163795)

English

Apoptosis induced in synchronized human immunodeficiency virus type 1-infected primary peripheral blood mononuclear cells is detected after the peak of CD4+ T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein

scientific article published on September 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 September 2017

Apoptosis induced in synchronized human immunodeficiency virus type 1-infected primary peripheral blood mononuclear cells is detected after the peak of CD4+ T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

author name string

Victoria A Lawson

1

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Katherine A Silburn

2

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Paul R Gorry

3

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Geza Paukovic

4

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Damian F J Purcell

5

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Alison L Greenway

6

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Dale A McPhee

7

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Europe PubMed Central

PubMed publication ID

9 September 2017

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publication date

1 September 2004

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Europe PubMed Central

PubMed publication ID

9 September 2017

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Europe PubMed Central

PubMed publication ID

9 September 2017

327

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Europe PubMed Central

PubMed publication ID

9 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

70-82

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

2 references

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.012

7 January 2021

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7 January 2021

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The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.012

7 January 2021

Mitochondria in HIV-1-induced apoptosis.

1 reference

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7 January 2021

To kill or be killed: viral evasion of apoptosis

1 reference

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7 January 2021

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

1 reference

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7 January 2021

Death of CD4(+) T-cell lines caused by human immunodeficiency virus type 1 does not depend on caspases or apoptosis

1 reference

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7 January 2021

Activation-associated necrosis in human immunodeficiency virus infection

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The interaction of macrophage and non-macrophage tropic isolates of HIV-1 with thymic and tonsillar dendritic cells in vitro

1 reference

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Low levels of co-receptor CCR5 are sufficient to permit HIV envelope-mediated fusion with resting CD4 T cells

1 reference

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The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

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Antigen-stimulated apoptotic T-cell death in HIV infection is selective for CD4+ T cells, modulated by cytokines and effected by lymphotoxin.

1 reference

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Cell turnover and cell tropism in HIV-1 infection.

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Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

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Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo

1 reference

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7 January 2021

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

1 reference

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7 January 2021

HIV-1 directly kills CD4+ T cells by a Fas-independent mechanism

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Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

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Construction and in vitro properties of HIV-1 mutants with deletions in "nonessential" genes

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Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

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7 January 2021

Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

1 reference

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Persistence of dual-tropic HIV-1 in an individual homozygous for the CCR5 Delta 32 allele.

1 reference

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7 January 2021

Apoptosis in AIDS. Genetic control and relevance for AIDS pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.012

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Human immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis.

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HIV-1 Nef control of cell signalling molecules: multiple strategies to promote virus replication

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Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals

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Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.

1 reference

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Susceptibility of peripheral blood mononuclear cells to apoptosis is correlated to plasma HIV load

1 reference

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

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Kinetics of HIV-1 replication and intracellular accumulation of particles in HTLV-I-transformed cells

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Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

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7 January 2021

Human immunodeficiency virus 1 envelope-initiated G2-phase programmed cell death

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Cytopathicity of human immunodeficiency virus type 1 primary isolates depends on coreceptor usage and not patient disease status

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Importance of membrane fusion mediated by human immunodeficiency virus envelope glycoproteins for lysis of primary CD4-positive T cells

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Membrane expression of HIV envelope glycoproteins triggers apoptosis in CD4 cells

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Membrane-expressed HIV envelope glycoprotein heterodimer is a powerful inducer of cell death in uninfected CD4+ target cells

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Cytopathic killing of peripheral blood CD4(+) T lymphocytes by human immunodeficiency virus type 1 appears necrotic rather than apoptotic and does not require env.

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Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: role for Nef and immune activation in viral persistence

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The end of the (cell) line: methods for the study of apoptosis in vitro.

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Programmed death of T cells in HIV-1 infection

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Isolation of HIV from Australian patients with AIDS, AIDS related conditions and healthy antibody positive individuals

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Mechanism of apoptosis in peripheral blood mononuclear cells of HIV-infected patients

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Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI.

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CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue

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Both necrosis and apoptosis contribute to HIV-1-induced killing of CD4 cells

1 reference

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Interactions of HIV-1 NEF with cellular signal transducing proteins

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Apoptosis in AIDS.

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Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

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Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators

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Interleukin-2 induction of T-cell G1 progression and c-myb expression

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Construction and characterization of a stable full-length macrophage-tropic HIV type 1 molecular clone that directs the production of high titers of progeny virions

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Studies with GFP-Vpr fusion proteins: induction of apoptosis but ablation of cell-cycle arrest despite nuclear membrane or nuclear localization

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CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

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Polyclonal proliferation and apoptosis of CCR5+ T lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2.

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10.1016/J.VIROL.2004.06.012

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Europe PubMed Central

PubMed publication ID

9 September 2017

release_fzseogl74zhchanr5oaxjur6py

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9 September 2017

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