(Q39177371)

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Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding mechanism

scientific article published on May 2013

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scholarly article

1 reference

Europe PubMed Central

9 September 2017

Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding mechanism (English)

1 reference

Europe PubMed Central

9 September 2017

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Cristina P Matos

4

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Ana Isabel Tomaz

12

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Fernanda Marques

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10

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João Costa Pessoa

6

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object named as

Isabel Santos

7

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author name string

Bruno Demoro

1

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Europe PubMed Central

9 September 2017

Rodrigo F M de Almeida

2

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Europe PubMed Central

9 September 2017

Lucía Otero

5

1 reference

Europe PubMed Central

9 September 2017

Alejandra Rodríguez

8

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Europe PubMed Central

9 September 2017

Virtudes Moreno

9

1 reference

Europe PubMed Central

9 September 2017

Dinorah Gambino

11

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Europe PubMed Central

9 September 2017

language of work or name

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publication date

1 May 2013

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Europe PubMed Central

9 September 2017

Dalton Transactions

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Europe PubMed Central

9 September 2017

42

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Europe PubMed Central

9 September 2017

19

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Europe PubMed Central

9 September 2017

7131-7146

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Europe PubMed Central

9 September 2017

INHIBITION OF CELL DIVISION IN ESCHERICHIA COLI BY ELECTROLYSIS PRODUCTS FROM A PLATINUM ELECTRODE

1 reference

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21 January 2018

Recent developments in the field of tumor-inhibiting metal complexes.

1 reference

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21 January 2018

The resurgence of platinum-based cancer chemotherapy

1 reference

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Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates

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21 January 2018

Ruthenium-based chemotherapeutics: are they ready for prime time?

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21 January 2018

Arene ruthenium complexes as anticancer agents

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21 January 2018

Recent developments in ruthenium anticancer drugs

1 reference

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21 January 2018

New trends for metal complexes with anticancer activity

1 reference

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21 January 2018

KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients

1 reference

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21 January 2018

Ruthenium antimetastatic agents

1 reference

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21 January 2018

Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes

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In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

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Selective cytotoxic Ru(II) arene Cp* complex salts [R-PhRuCp*](+)X(-) for X = BF4(-), PF6(-), and BPh4(-).

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Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor.

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Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands.

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Studies of the Antiproliferative Activity of Ruthenium (II) Cyclopentadienyl-Derived Complexes with Nitrogen Coordinated Ligands.

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21 January 2018

Thiophenolato-bridged dinuclear arene ruthenium complexes: a new family of highly cytotoxic anticancer agents.

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Targeted and multifunctional arene ruthenium chemotherapeutics

1 reference

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21 January 2018

The wide pharmacological versatility of semicarbazones, thiosemicarba-zones and their metal complexes.

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21 January 2018

In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones.

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21 January 2018

Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives

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21 January 2018

Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 1. Discovery and optimization of salicylaldehyde thiosemicarbazone thrombopoietin mimics.

1 reference

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21 January 2018

2-Acetylpyridine thiosemicarbazones. 4. Complexes with transition metals as antimalarial and antileukemic agents

1 reference

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21 January 2018

Studies on the mechanism of hypoxic selectivity in copper bis(thiosemicarbazone) radiopharmaceuticals.

1 reference

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21 January 2018

Organometallic ruthenium complexes with thiosemicarbazone ligands: Synthesis, structure and cytotoxicity of [(eta-p-cymene)Ru(NS)Cl] (NS = 9-anthraldehyde thiosemicarbazones).

1 reference

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21 January 2018

Half-sandwich ruthenium–arene complexes with thiosemicarbazones: synthesis and biological evaluation of [(η⁶-p-cymene)Ru(piperonal thiosemicarbazones)Cl]Cl complexes

1 reference

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21 January 2018

New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents.

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21 January 2018

5-Nitro-2-furyl derivative actives against Trypanosoma cruzi: preliminary in vivo studies.

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21 January 2018

Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents

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21 January 2018

Effect of ruthenium complexation on trypanocidal activity of 5-nitrofuryl containing thiosemicarbazones.

1 reference

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21 January 2018

In silico prediction of drug-binding strengths to human serum albumin

1 reference

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21 January 2018

The extraordinary ligand binding properties of human serum albumin

1 reference

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21 January 2018

Structural basis of the drug-binding specificity of human serum albumin

1 reference

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21 January 2018

In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands

1 reference

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21 January 2018

Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles

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21 January 2018

Tumor-selective delivery of macromolecular drugs via the EPR effect: background and future prospects

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21 January 2018

Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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21 January 2018

Microtubule-binding agents: a dynamic field of cancer therapeutics

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Integrins as therapeutic targets: lessons and opportunities

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Ligand-independent activation of c-Met by fibronectin and α(5)β(1)-integrin regulates ovarian cancer invasion and metastasis

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Mitosis as an anti-cancer target

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21 January 2018

Arene control over thiolate to sulfinate oxidation in albumin by organometallic ruthenium anticancer complexes.

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21 January 2018

Conformational changes in human serum albumin studied by fluorescence and absorption spectroscopy. Distance measurements as a function of pH and fatty acids

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Complexes between fluorescent cholic acid derivatives and human serum albumin. a photophysical approach to investigate the binding behavior

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FRET analysis of domain formation and properties in complex membrane systems

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21 January 2018

Formation of ceramide/sphingomyelin gel domains in the presence of an unsaturated phospholipid: a quantitative multiprobe approach.

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21 January 2018

Rapid confirmation and revision of the primary structure of bovine serum albumin by ESIMS and Frit-FAB LC/MS

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21 January 2018

Intestinal permeability to polyethylene glycol 4000 and porcine albumin in piglets infected with transmissible gastroenteritis virus

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21 January 2018

Study of thermal dynamics of defatted bovine serum albumin in D2O solution by Fourier transform infrared spectra and evolving factor analysis.

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Hyperquad simulation and speciation (HySS): a utility program for the investigation of equilibria involving soluble and partially soluble species

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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21 January 2018

In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model.

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21 January 2018

DNA interaction and cytotoxicity studies of new ruthenium(II) cyclopentadienyl derivative complexes containing heteroaromatic ligands

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Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets

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21 January 2018

Transport of Therapeutic Vanadium and Ruthenium Complexes by Blood Plasma Components

1 reference

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21 January 2018

Identifiers

10.1039/C3DT00028A

1 reference

Europe PubMed Central

9 September 2017

1 reference

Europe PubMed Central

9 September 2017

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