(Q39198219)

9 September 2017

title

Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma (English)

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9 September 2017

Roman Reinartz

10

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Jerome Mertens

Jerome Mertens

7

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Philipp Koch

Philipp Koch

6

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Harald Neumann

Harald Neumann

16

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Gunther Hartmann

Gunther Hartmann

20

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Martin Schlee

15

Martin Schlee

1 reference

9 September 2017

19

Oliver Brüstle

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9 September 2017

11

Anja Wieland

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9 September 2017

3

Daniel Trageser

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9 September 2017

22

Björn Scheffler

1 reference

9 September 2017

Martin Glas

1

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9 September 2017

Christoph Coch

2

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9 September 2017

Juliane Dassler

4

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9 September 2017

Matthias Simon

5

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9 September 2017

Tamara Quandel

8

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9 September 2017

Raphaela Gorris

9

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9 September 2017

Marec Von Lehe

12

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9 September 2017

Annette Pusch

13

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9 September 2017

Kristin Roy

14

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9 September 2017

Rolf Fimmers

17

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9 September 2017

Ulrich Herrlinger

18

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9 September 2017

Robert Besch

21

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9 September 2017

publication date

1 June 2013

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9 September 2017

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9 September 2017

volume

31

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9 September 2017

issue

6

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9 September 2017

page(s)

1064-1074

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

9 September 2017

cites work

1 reference

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

21 January 2018

1 reference

Immune surveillance of tumors

21 January 2018

1 reference

Heterogeneity maintenance in glioblastoma: a social network

21 January 2018

1 reference

Innate recognition of viruses

21 January 2018

1 reference

EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice

21 January 2018

1 reference

Immunostimulants for malignant gliomas

21 January 2018

1 reference

A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma

21 January 2018

1 reference

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

21 January 2018

1 reference

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

1 reference

Targeted activation of RNA helicase retinoic acid-inducible gene-I induces proimmunogenic apoptosis of human ovarian cancer cells

21 January 2018

1 reference

Transcriptional re-programming of primary macrophages reveals distinct apoptotic and anti-tumoral functions of IRF-3 and IRF-7.

21 January 2018

1 reference

Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells

21 January 2018

1 reference

Derivation and large-scale expansion of multipotent astroglial neural progenitors from adult human brain.

21 January 2018

1 reference

A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration

21 January 2018

1 reference

Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons

21 January 2018

1 reference

Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells.

21 January 2018

1 reference

Phenotypic and functional characterization of adult brain neuropoiesis

21 January 2018

1 reference

Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cells

21 January 2018

1 reference

Induction of anti-glioma natural killer cell response following multiple low-dose intracerebral CpG therapy

21 January 2018

1 reference

CD107a as a functional marker for the identification of natural killer cell activity.

21 January 2018

1 reference

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

The neurobiology of gliomas: from cell biology to the development of therapeutic approaches

21 January 2018

1 reference

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

21 January 2018

1 reference

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens

21 January 2018

1 reference

Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents

21 January 2018

1 reference

Self-renewal does not predict tumor growth potential in mouse models of high-grade glioma.

21 January 2018

1 reference

Current concepts and management of glioblastoma

21 January 2018

1 reference

Immunotherapy coming of age: what will it take to make it standard of care for glioblastoma?

21 January 2018

1 reference

Immunotherapy of malignant brain tumors

21 January 2018

1 reference

5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

21 January 2018

1 reference

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/STEM.1350

1 reference

9 September 2017

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