(Q39207741)

10 September 2017

title

Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies (English)

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10 September 2017

17

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10 September 2017

R Natrajan

4

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Alan Ashworth

18

object named as

A Ashworth

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10 September 2017

3

A Mackay

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10 September 2017

K-K Shiu

1

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10 September 2017

D Wetterskog

2

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10 September 2017

M Lambros

5

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10 September 2017

D Sims

6

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10 September 2017

I Bajrami

7

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10 September 2017

R Brough

8

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10 September 2017

J Frankum

9

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10 September 2017

R Sharpe

10

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10 September 2017

C Marchio

11

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10 September 2017

H Horlings

12

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10 September 2017

F Reyal

13

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10 September 2017

M van der Vijver

14

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10 September 2017

N Turner

15

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10 September 2017

J S Reis-Filho

16

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10 September 2017

language of work or name

English

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publication date

21 January 2013

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10 September 2017

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10 September 2017

volume

33

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10 September 2017

issue

5

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10 September 2017

page(s)

619-631

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

10 September 2017

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High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer

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DNA amplifications in breast cancer: genotypic-phenotypic correlations

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Novel patterns of genome rearrangement and their association with survival in breast cancer

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Genome profiling of ERBB2-amplified breast cancers

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An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers

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Comparative genomic hybridisation arrays: high-throughput tools to determine targeted therapy in breast cancer

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Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

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RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy

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Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis.

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The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma

21 January 2018

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Identification of HTF (HER2 transcription factor) as an AP-2 (activator protein-2) transcription factor and contribution of the HTF binding site to ERBB2 gene overexpression

21 January 2018

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Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells

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Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers.

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Overexpression of TFAP2C in invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival

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Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells

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AP-2gamma promotes proliferation in breast tumour cells by direct repression of the CDKN1A gene

21 January 2018

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Distal ERBB2 promoter fragment displays specific transcriptional and nuclear binding activities in ERBB2 overexpressing breast cancer cells

21 January 2018

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Cancer. Addiction to oncogenes--the Achilles heal of cancer

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Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+ breast cancer patients

21 January 2018

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21 January 2018

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Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer.

21 January 2018

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21 January 2018

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21 January 2018

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The genomic profile of HER2-amplified breast cancers: the influence of ER status

21 January 2018

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EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer

21 January 2018

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Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines

21 January 2018

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21 January 2018

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31 March 2020

Identifiers

DOI

10.1038/ONC.2012.625

1 reference

Dimensions Publication ID

10 September 2017

1012404890

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Fatcat ID

release_6o2xzhuderc57bhyrtnwvv4n7m

0 references

1 reference