(Q39218252)

10 September 2017

title

Human T-cell leukemia virus type 1 Tax protein interacts with and mislocalizes the PDZ domain protein MAGI-1. (English)

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Human T-lymphotropic virus 1

10 September 2017

main subject

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Grace Naswa Makokha

1

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author name string

Masahiko Takahashi

2

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10 September 2017

Masaya Higuchi

3

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10 September 2017

Suguru Saito

4

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10 September 2017

Yuetsu Tanaka

5

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10 September 2017

Masahiro Fujii

6

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10 September 2017

publication date

30 January 2013

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10 September 2017

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10 September 2017

volume

104

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10 September 2017

issue

3

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10 September 2017

page(s)

313-320

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Human T cell lymphotropic virus type I genomic expression and impact on intracellular signaling pathways during neurodegenerative disease and leukemia

10 September 2017

cites work

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Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

21 January 2018

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Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation

21 January 2018

1 reference

Molecular mechanisms of cellular transformation by HTLV-1 Tax.

21 January 2018

1 reference

The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice

21 January 2018

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Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I.

21 January 2018

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The Tax protein of HTLV-1 promotes oncogenesis in not only immature T cells but also mature T cells.

21 January 2018

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The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins

21 January 2018

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Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control

21 January 2018

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PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein augments the transforming activity in a rat fibroblast cell line

21 January 2018

1 reference

PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line

21 January 2018

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PDZ binding motif of HTLV-1 Tax promotes virus-mediated T-cell proliferation in vitro and persistence in vivo

21 January 2018

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Comparative biology of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2

21 January 2018

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Deregulation of cell-signaling pathways in HTLV-1 infection

21 January 2018

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Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis

21 January 2018

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Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

Human and primate tumour viruses use PDZ binding as an evolutionarily conserved mechanism of targeting cell polarity regulators

21 January 2018

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Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

21 January 2018

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PDZ proteins organize synaptic signaling pathways

21 January 2018

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PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane

21 January 2018

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A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands

21 January 2018

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Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation

21 January 2018

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Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

21 January 2018

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Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

21 January 2018

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Cell polarity proteins: common targets for tumorigenic human viruses

21 January 2018

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Human T-cell leukemia virus type 1 Tax induces an aberrant clustering of the tumor suppressor Scribble through the PDZ domain-binding motif dependent and independent interaction

21 January 2018

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Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene

21 January 2018

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HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation

21 January 2018

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The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

21 January 2018

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Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human T-cell leukemia virus type 1 Tax protein

21 January 2018

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MAGI-1, a membrane-associated guanylate kinase with a unique arrangement of protein-protein interaction domains

21 January 2018

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Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins

21 January 2018

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A systematic analysis of human papillomavirus (HPV) E6 PDZ substrates identifies MAGI-1 as a major target of HPV type 16 (HPV-16) and HPV-18 whose loss accompanies disruption of tight junctions

21 January 2018

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Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth

21 January 2018

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Human T-cell leukemia virus type 2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax.

21 January 2018

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Cooperation of NF-kappaB2/p100 activation and the PDZ domain binding motif signal in human T-cell leukemia virus type 1 (HTLV-1) Tax1 but not HTLV-2 Tax2 is crucial for interleukin-2-independent growth transformation of a T-cell line

21 January 2018

1 reference

Production of a recombinant human T-cell leukemia virus type-I trans-activator (tax1) antigen and its utilization for generation of monoclonal antibodies against various epitopes on the tax1 antigen

21 January 2018

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A 10-amino acid domain within human T-cell leukemia virus type 1 and type 2 tax protein sequences is responsible for their divergent subcellular distribution

21 January 2018

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Human T-cell leukemia virus type 1 Tax oncoprotein induces and interacts with a multi-PDZ domain protein, MAGI-3.

21 January 2018

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The PDZ domain-binding motif of the human T cell leukemia virus type 1 tax protein induces mislocalization of the tumor suppressor hScrib in T cells

21 January 2018

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The PDZ domain binding motif (PBM) of human T-cell leukemia virus type 1 Tax can be substituted by heterologous PBMs from viral oncoproteins during T-cell transformation

21 January 2018

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SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

21 January 2018

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Downregulation of MAGI1 associates with poor prognosis of hepatocellular carcinoma.

21 January 2018

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Human T cell leukemia virus type 2 (HTLV-2) Tax2 has a dominant activity over HTLV-1 Tax1 to immortalize human CD4+ T cells

21 January 2018

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12 December 2020

Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture

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12 December 2020

Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness.

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12 December 2020

Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone

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12 December 2020

Proliferative response of Tax1-transduced primary human T cells to anti-CD3 antibody stimulation by an interleukin-2-independent pathway.

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12 December 2020

The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes

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12 December 2020

Human T-cell leukemia virus type 1 tax protein abrogates interleukin-2 dependence in a mouse T-cell line.

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12 December 2020

Identifiers

DOI

10.1111/CAS.12087

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10 September 2017

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