(Q39221863)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23966081%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Neuroprotective, anti-amyloidogenic and neurotrophic effects of apigenin in an Alzheimer's disease mouse model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23966081%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

0 references

Le Zhao

1

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8 March 2020

Jun-Li Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23966081%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Rui Liu

3

1 reference

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8 March 2020

Xiao-Xu Li

4

1 reference

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8 March 2020

Jian-Fei Li

5

1 reference

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8 March 2020

Lu Zhang

6

1 reference

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8 March 2020

language of work or name

English

0 references

publication date

19 August 2013

1 reference

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8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23966081%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

volume

18

1 reference

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8 March 2020

issue

8

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8 March 2020

page(s)

9949-9965

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23966081%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

8 March 2020

copyright license

start time

19 August 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Pathways towards and away from Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

The role of neurotrophins in brain aging: a perspective in honor of Regino Perez-Polo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Anti-influenza virus activities of flavonoids from the medicinal plant Elsholtzia rugulosa

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Protection of apigenin against kainate-induced excitotoxicity by anti-oxidative effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Novel neuronal phenotypes from neural progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Vasodilatory action mechanisms of apigenin isolated from Apium graveolens in rat thoracic aorta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Apigenin modulates GABAergic and glutamatergic transmission in cultured cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Apigenin attenuates copper-mediated β-amyloid neurotoxicity through antioxidation, mitochondrion protection and MAPK signal inactivation in an AD cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

beta-Amyloid protein-induced Alzheimer's disease animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Bilateral injections of amyloid-beta 25-35 into the amygdala of young Fischer rats: behavioral, neurochemical, and time dependent histopathological effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Protective effect of flavonoids against aging- and lipopolysaccharide-induced cognitive impairment in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Apigenin reduces human insulin fibrillation in vitro and protects SK-N-MC cells against insulin amyloids

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Flavonols and flavones as BACE-1 inhibitors: structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

In vitro anti-inflammatory effect of apigenin in the Helicobacter pylori-infected gastric adenocarcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Oxidative damage in Alzheimer's.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Oxidative stress hypothesis in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Prevention of cellular ROS damage by isovitexin and related flavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Measurement of xanthine oxidase inhibition activity of phenolics and flavonoids with a modified cupric reducing antioxidant capacity (CUPRAC) method.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Quercetin protects against the Aβ(25-35)-induced amnesic injury: involvement of inactivation of rage-mediated pathway and conservation of the NVU.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Molecular enhancement of memory formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

CRE-mediated gene transcription in neocortical neuronal plasticity during the developmental critical period

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18089949

Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

21 January 2018

1 reference

12 December 2020

Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice

1 reference

12 December 2020

Lipid peroxidation and oxidative imbalance: early functional events in Alzheimer's disease.

1 reference

12 December 2020

Amyloid-β production via cleavage of amyloid-β protein precursor is modulated by cell density

1 reference

12 December 2020

Accumulation of insoluble amyloid-β in down's syndrome is associated with increased BACE-1 and neprilysin activities.

1 reference

12 December 2020

The flavonoid apigenin protects brain neurovascular coupling against amyloid-β₂₅₋₃₅-induced toxicity in mice.

1 reference

12 December 2020

L-3-n-butylphthalide reduces tau phosphorylation and improves cognitive deficits in AβPP/PS1-Alzheimer's transgenic mice

1 reference

12 December 2020

Attenuation of oxidative damage and inflammatory responses by apigenin given to mice after irradiation

1 reference

12 December 2020

Rapid, reversible impairment of synaptic signaling in cultured cortical neurons by exogenously-applied amyloid-β.

1 reference

12 December 2020

DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay.

1 reference

12 December 2020

Amyloid beta-peptide inhibits high-affinity choline uptake and acetylcholine release in rat hippocampal slices.

1 reference

12 December 2020

10.3390/MOLECULES18089949

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23966081%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23966081%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

23966081

1 reference