(Q39229600)

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High expression of crystallin αB represents an independent molecular marker for unfavourable ovarian cancer patient outcome and impairs TRAIL- and cisplatin-induced apoptosis in human ovarian cancer cells.

scientific article published on 27 December 2012

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20 February 2020

High expression of crystallin αB represents an independent molecular marker for unfavourable ovarian cancer patient outcome and impairs TRAIL- and cisplatin-induced apoptosis in human ovarian cancer cells (English)

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20 February 2020

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20 February 2020

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20 February 2020

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20 February 2020

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20 February 2020

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Alfons Meindl

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20 February 2020

Barbara Schmalfeldt

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Barbara Schmalfeldt

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20 February 2020

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Juliane Ramser

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20 February 2020

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Felix Hilpert

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20 February 2020

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Ute Reuning

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20 February 2020

Martina Rudelius

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20 February 2020

Tibor Schuster

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20 February 2020

Aaron Becker V Ros

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20 February 2020

Marion Kiechle

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20 February 2020

Matthias Dürst

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20 February 2020

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27 December 2012

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20 February 2020

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13

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International Journal of Cancer

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20 February 2020

132

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20 February 2020

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20 February 2020

2820-2832

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20 February 2020

Cancer statistics, 2010

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27975

21 January 2018

Carcinoma of the ovary. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer

1 reference

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21 January 2018

Ovarian cancer: strategies for overcoming resistance to chemotherapy

1 reference

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21 January 2018

Too much of a good thing: suicide prevention promotes chemoresistance in ovarian carcinoma

1 reference

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21 January 2018

Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis.

1 reference

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21 January 2018

Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27975

21 January 2018

Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27975

21 January 2018

The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27975

21 January 2018

The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation

1 reference

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21 January 2018

The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27975

21 January 2018

Efficacy of anti-death receptor 5 (DR5) antibody (TRA-8) against primary human ovarian carcinoma using a novel ex vivo tissue slice model.

1 reference

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21 January 2018

Enhanced antitumor efficacy of a DR5-specific TRAIL variant over recombinant human TRAIL in a bioluminescent ovarian cancer xenograft model.

1 reference

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21 January 2018

Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1.

1 reference

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21 January 2018

A phase 1 study of mapatumumab (fully human monoclonal antibody to TRAIL-R1) in patients with advanced solid malignancies.

1 reference

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21 January 2018

Gene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia.

1 reference

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21 January 2018

Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

1 reference

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21 January 2018

Integrin alphavbeta3 upregulates integrin-linked kinase expression in human ovarian cancer cells via enhancement of ILK gene transcription.

1 reference

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21 January 2018

Morphological, immunohistochemical and biochemical characterization of 6 newly established human ovarian carcinoma cell lines

1 reference

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21 January 2018

Ovarian cancer cell proliferation and motility is induced by engagement of integrin alpha(v)beta3/Vitronectin interaction

1 reference

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21 January 2018

Check your cultures! A list of cross-contaminated or misidentified cell lines

1 reference

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21 January 2018

Integrin alpha(v)beta(3)/vitronectin interaction affects expression of the urokinase system in human ovarian cancer cells

1 reference

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21 January 2018

Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer

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21 January 2018

AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer

1 reference

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21 January 2018

alphaB-crystallin is a novel predictor of resistance to neoadjuvant chemotherapy in breast cancer

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21 January 2018

Small heat-shock protein family: function in health and disease.

1 reference

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21 January 2018

Is TRAIL the holy grail of cancer therapy?

1 reference

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21 January 2018

TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges

1 reference

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21 January 2018

The inhibition of Bid expression by Akt leads to resistance to TRAIL-induced apoptosis in ovarian cancer cells

1 reference

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21 January 2018

Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27975

21 January 2018

Malignant ascites protect against TRAIL-induced apoptosis by activating the PI3K/Akt pathway in human ovarian carcinoma cells

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27975

21 January 2018

Ovarian cancer ascites protects from TRAIL-induced cell death through alphavbeta5 integrin-mediated focal adhesion kinase and Akt activation

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27975

21 January 2018

The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27975

21 January 2018

Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients

1 reference

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21 January 2018

Alpha B-Crystallin, a New Independent Marker for Poor Prognosis in Head and Neck Cancer

1 reference

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21 January 2018

Identifiers

10.1002/IJC.27975

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225306%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

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Europe PubMed Central

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20 February 2020

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