(Q39233165)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

title

Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

main subject

hypoxia

0 references

neoplastic stem cells

1 reference

1 reference

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Shoukat Dedhar

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

author name string

F E Lock

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

P C McDonald

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Y Lou

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

I Serrano

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

S C Chafe

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

C Ostlund

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

S Aparicio

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

C T Supuran

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

language of work or name

English

0 references

publication date

3 December 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

issue

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

page(s)

5210-5219

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2012.550

19 February 2020

exact match

0 references

cites work

Tumour stem cells and drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Cancer stem cells in solid tumors: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Stem cells, cancer, and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Brca1 breast tumors contain distinct CD44+/CD24- and CD133+ cells with cancer stem cell characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Determining mammosphere-forming potential: application of the limiting dilution analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24- phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Primary breast cancer patients with high risk clinicopathologic features have high percentages of bone marrow epithelial cells with ALDH activity and CD44⁺CD24lo cancer stem cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Identification of tumorsphere- and tumor-initiating cells in HER2/Neu-induced mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Regulation of mTORC1 signaling by pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

An emerging role for TOR signaling in mammalian tissue and stem cell physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

mTOR-targeted therapy of cancer with rapamycin derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Mutual regulation of hypoxia-inducible factor and mammalian target of rapamycin as a function of oxygen availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

The Spemann organizer gene, Goosecoid, promotes tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Targeting Notch to target cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Multiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44⁺ human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Identification of selective inhibitors of cancer stem cells by high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

21 January 2018

Hypoxia and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Oxygen regulates epithelial-to-mesenchymal transition: insights into molecular mechanisms and relevance to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Tuberin regulates E-cadherin localization: implications in epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

MET signaling regulates glioblastoma stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Three-dimensional culture models of normal and malignant breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

The invasive front in endometrial carcinoma: higher proliferation and associated derailment of cell cycle regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Malignant Pleural Effusion: Prognostic Factors for Survival and Response to Chemical Pleurodesis in a Series of 120 Cases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

Diagnostic value of metabolic phenotypes in malignant pleural effusions: expression of GLUT1 and CAIX by immunocytochemistry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.550

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.550

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23208505%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1 reference