(Q39240053)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28406335%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Clinical efficacy of edaravone for the treatment of amyotrophic lateral sclerosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28406335%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

17 March 2020

main subject

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28406335%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

author name string

Hideyuki Sawada

series ordinal

1

1 reference

10 September 2017

language of work or name

English

0 references

publication date

1 May 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28406335%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Pharmacotherapy

17 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28406335%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28406335%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28406335%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

page(s)

735-738

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28406335%20AND%20SRC:MED&resulttype=core&format=json

Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients

17 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

Genetics of sporadic ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

TDP-43-based animal models of neurodegeneration: new insights into ALS pathology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

Oxidative stress in ALS: key role in motor neuron injury and therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

Nicotine-induced protection against glutamate cytotoxicity. Nicotinic cholinergic receptor-mediated inhibition of nitric oxide formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

MPP(+) and glutamate in the degeneration of nigral dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

Edaravone, a potent free radical scavenger, reacts with peroxynitrite to produce predominantly 4-NO-edaravone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

Treatment with edaravone, initiated at symptom onset, slows motor decline and decreases SOD1 deposition in ALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

Edaravone, a Free Radical Scavenger, Delayed Symptomatic and Pathological Progression of Motor Neuron Disease in the Wobbler Mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14656566.2017.1319937

10.1080/14656566.2017.1319937

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28406335%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference