(Q39242131)

10 September 2017

The MYC-associated protein CDCA7 is phosphorylated by AKT to regulate MYC-dependent apoptosis and transformation (English)

1 reference

10 September 2017

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R Montgomery Gill

1

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10 September 2017

Timothy V Gabor

series ordinal

2

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10 September 2017

Amber L Couzens

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3

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10 September 2017

Michael P Scheid

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4

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10 September 2017

language of work or name

English

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publication date

19 November 2012

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Molecular and Cellular Biology

10 September 2017

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10 September 2017

33

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10 September 2017

3

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10 September 2017

498-513

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describes a project that uses

10 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3554214/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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10 September 2017

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10 September 2017

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MYC in oncogenesis and as a target for cancer therapies

10 September 2017

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MYC regulation of a "poor-prognosis" metastatic cancer cell state

10 September 2017

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Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT.

10 September 2017

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The ups and downs of Myc biology

10 September 2017

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Reflecting on 25 years with MYC.

10 September 2017

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Phosphorylation of MEKK3 at threonine 294 promotes 14-3-3 association to inhibit nuclear factor kappaB activation

10 September 2017

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Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression

10 September 2017

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Identifying synergistic regulation involving c-Myc and sp1 in human tissues

10 September 2017

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The Oscar-worthy role of Myc in apoptosis

10 September 2017

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Monoamine oxidase A and repressor R1 are involved in apoptotic signaling pathway

10 September 2017

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JPO1/CDCA7, a novel transcription factor E2F1-induced protein, possesses intrinsic transcriptional regulator activity

10 September 2017

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ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.

10 September 2017

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The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells

10 September 2017

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Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

10 September 2017

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The Myc target gene JPO1/CDCA7 is frequently overexpressed in human tumors and has limited transforming activity in vivo

10 September 2017

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Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells

10 September 2017

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Myc pathways provoking cell suicide and cancer

10 September 2017

1 reference

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The myc oncogene: MarvelouslY Complex

10 September 2017

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14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

10 September 2017

1 reference

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Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis

10 September 2017

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A novel c-Myc-responsive gene, JPO1, participates in neoplastic transformation

10 September 2017

1 reference

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The Myc/Max/Mad network and the transcriptional control of cell behavior

10 September 2017

1 reference

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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

The multiple roles of PTEN in tumor suppression

10 September 2017

1 reference

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Isolation of high-affinity peptide antagonists of 14-3-3 proteins by phage display

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

10 September 2017

1 reference

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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

10 September 2017

1 reference

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Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Regulation of neuronal survival by the serine-threonine protein kinase Akt

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

p53 and E2F-1 cooperate to mediate apoptosis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Effects of c-myc expression on cell cycle progression.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Induction of apoptosis in fibroblasts by c-myc protein

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

p19ARF directly and differentially controls the functions of c-Myc independently of p53.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Mediation of c-Myc-induced apoptosis by p53.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

c-Myc cooperates with activated Ras to induce the cdc2 promoter

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554214

The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene

21 August 2018

1 reference

12 December 2020

Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block

1 reference

12 December 2020

PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies

1 reference

12 December 2020

Kinetic characterization of the human retinoblastoma protein bipartite nuclear localization sequence (NLS) in vivo and in vitro. A comparison with the SV40 large T-antigen NLS

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.00276-12

1 reference

10 September 2017

1 reference

10 September 2017

PubMed publication ID

23166294

1 reference