(Q39244069)

10 September 2017

title

Laquinimod delays and suppresses nephritis in lupus-prone mice and affects both myeloid and lymphoid immune cells (English)

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10 September 2017

Elaine V Lourenço

1

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10 September 2017

Maida Wong

2

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10 September 2017

Bevra H Hahn

3

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10 September 2017

M Fernando Palma-Diaz

4

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10 September 2017

Brian J Skaggs

5

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10 September 2017

publication date

1 March 2014

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10 September 2017

published in

Arthritis & Rheumatology

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10 September 2017

volume

66

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10 September 2017

issue

3

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10 September 2017

page(s)

674-685

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Lupus nephritis: lessons from murine models

10 September 2017

cites work

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American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis

21 January 2018

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Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis

21 January 2018

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Local macrophage proliferation in human glomerulonephritis

21 January 2018

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Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis

21 January 2018

1 reference

Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity

21 January 2018

1 reference

Placebo-controlled trial of oral laquinimod for multiple sclerosis

21 January 2018

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Dysfunctional, pro-inflammatory HDL directly upregulates monocyte PDGFRβ, chemotaxis and TNFα production

21 January 2018

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Modulation of autoimmune demyelination by laquinimod via induction of brain-derived neurotrophic factor.

21 January 2018

1 reference

Subsets of myeloid-derived suppressor cells in tumor-bearing mice

21 January 2018

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Myeloid-derived suppressor cell heterogeneity and subset definition.

21 January 2018

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Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

21 January 2018

1 reference

The biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity

21 January 2018

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The chemokine system in diverse forms of macrophage activation and polarization

21 January 2018

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Macrophage diversity in renal injury and repair.

21 January 2018

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The potential role of Th17 cells and Th17-related cytokines in the pathogenesis of lupus nephritis

21 January 2018

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The role of IL-23/IL-17 axis in lupus nephritis

21 January 2018

1 reference

21 January 2018

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Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

21 January 2018

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Kinetics of proinflammatory monocytes in a model of multiple sclerosis and its perturbation by laquinimod.

21 January 2018

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The new orally active immunoregulator laquinimod (ABR-215062) effectively inhibits development and relapses of experimental autoimmune encephalomyelitis

21 January 2018

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Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

21 January 2018

1 reference

Myeloid derived suppressor cells in human diseases

21 January 2018

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Myeloid-derived suppressor cells as regulators of the immune system

21 January 2018

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Innate immune CD11b+Gr-1+ cells, suppressor cells, affect the immune response during Theiler's virus-induced demyelinating disease

21 January 2018

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Myeloid-derived suppressor cells in parasitic infections

21 January 2018

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Myeloid-derived suppressor cells prevent type 1 diabetes in murine models

21 January 2018

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Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function

21 January 2018

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Myeloid-derived suppressor cells play crucial roles in the regulation of mouse collagen-induced arthritis

21 January 2018

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Mouse CD11b+Gr-1+ myeloid cells can promote Th17 cell differentiation and experimental autoimmune encephalomyelitis

21 January 2018

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Dose translation from animal to human studies revisited

21 January 2018

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Pharmacokinetics, tolerability, and preliminary efficacy of paquinimod (ABR-215757), a new quinoline-3-carboxamide derivative: studies in lupus-prone mice and a multicenter, randomized, double-blind, placebo-controlled, repeat-dose, dose-ranging stu

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.38259

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10 September 2017

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