(Q46463050)

22 December 2017

title

Type II monocytes modulate T cell-mediated central nervous system autoimmune disease (English)

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22 December 2017

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8

Olaf Stüve

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22 December 2017

Martin S Weber

1

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22 December 2017

Thomas Prod'homme

2

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22 December 2017

Sawsan Youssef

3

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22 December 2017

Shannon E Dunn

4

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22 December 2017

Cynthia D Rundle

5

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22 December 2017

Linda Lee

6

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22 December 2017

Juan C Patarroyo

7

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22 December 2017

Raymond A Sobel

9

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22 December 2017

Lawrence Steinman

10

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22 December 2017

Scott S Zamvil

11

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22 December 2017

language of work or name

English

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publication date

5 August 2007

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22 December 2017

published in

Nature Medicine

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22 December 2017

volume

13

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22 December 2017

issue

8

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22 December 2017

page(s)

935-943

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22 December 2017

https://scigraph.springernature.com/pub.10.1038/nm1620

exact match

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cites work

Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group

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Mechanisms of action of glatiramer acetate in multiple sclerosis

21 January 2018

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Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis.

21 January 2018

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Glatiramer Acetate (Copolymer-1, Copaxone) Promotes Th2 Cell Development and Increased IL-10 Production Through Modulation of Dendritic Cells

21 January 2018

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STAT-1α and IFN-γ as Modulators of TNF-α Signaling in Macrophages: Regulation and Functional Implications of the TNF Receptor 1:STAT-1α Complex

21 January 2018

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Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance.

21 January 2018

1 reference

Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

21 January 2018

1 reference

Glatiramer acetate in multiple sclerosis: update on potential mechanisms of action

21 January 2018

1 reference

7 January 2021

Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells--specificity and promiscuity.

1 reference

7 January 2021

Copolymer 1 inhibits chronic relapsing experimental allergic encephalomyelitis induced by proteolipid protein (PLP) peptides in mice and interferes with PLP-specific T cell responses

1 reference

7 January 2021

Multiple sclerosis: comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells

1 reference

7 January 2021

Mechanisms of action of interferons and glatiramer acetate in multiple sclerosis

1 reference

7 January 2021

Glatiramer acetate (Copaxone) induces degenerate, Th2-polarized immune responses in patients with multiple sclerosis

1 reference

7 January 2021

Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis

1 reference

7 January 2021

Specific Th2 cells accumulate in the central nervous system of mice protected against experimental autoimmune encephalomyelitis by copolymer 1

1 reference

7 January 2021

Glatiramer acetate-specific T-helper 1- and 2-type cell lines produce BDNF: implications for multiple sclerosis therapy. Brain-derived neurotrophic factor

1 reference

7 January 2021

Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo

1 reference

7 January 2021

Impaired maturation and altered regulatory function of plasmacytoid dendritic cells in multiple sclerosis

1 reference

7 January 2021

Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity

1 reference

7 January 2021

TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

1 reference

7 January 2021

Inhibitory effects of incomplete Freund's adjuvant on experimental autoimmune encephalomyelitis

1 reference

7 January 2021

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

1 reference

7 January 2021

B7-2 (CD86) is essential for the development of IL-4-producing T cells

1 reference

7 January 2021

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

1 reference

7 January 2021

Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha.

1 reference

7 January 2021

STAT-1-mediated repression of monocyte interleukin-10 gene expression in vivo

1 reference

7 January 2021

Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis

1 reference

7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

7 January 2021

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

7 January 2021

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

1 reference

7 January 2021

Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis

1 reference

7 January 2021

Multiple immuno-regulatory defects in type-1 diabetes

1 reference

7 January 2021

Induction of CD4+CD25+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3

1 reference

7 January 2021

Effect of glatiramer acetate (Copaxone) on CD4+CD25high T regulatory cells and their IL-10 production in multiple sclerosis

1 reference

7 January 2021

Bystander suppression of experimental autoimmune encephalomyelitis by T cell lines and clones of the Th2 type induced by copolymer 1

1 reference

7 January 2021

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

7 January 2021

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

1 reference

7 January 2021

How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis

1 reference

7 January 2021

Dendritic cell vaccination for cancer therapy

1 reference

7 January 2021

pSTAT1, pSTAT3, and T-bet expression in peripheral blood mononuclear cells from relapsing-remitting multiple sclerosis patients correlates with disease activity.

1 reference

7 January 2021

Do Th2 cells mediate the effects of glatiramer acetate in experimental autoimmune encephalomyelitis?

1 reference

7 January 2021

Effect of treatment with copolymer 1 (Cop-1) on the in vivo and in vitro manifestations of experimental allergic encephalomyelitis (EAE)

1 reference

7 January 2021

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination.

1 reference

7 January 2021

Copolymer 1 inhibits experimental autoimmune uveoretinitis

1 reference

7 January 2021

Amelioration of experimental colitis by Copaxone is associated with class-II-restricted CD4 immune blocking

1 reference

7 January 2021

Mechanism of action of glatiramer acetate in multiple sclerosis and its potential for the development of new applications

1 reference

7 January 2021

T cells with two functional antigen-specific receptors

1 reference

7 January 2021

Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

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7 January 2021

Identifiers

DOI

10.1038/NM1620

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22 December 2017

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22 December 2017