(Q39259618)

10 September 2017

title

PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas (English)

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2

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16

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23

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28

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36

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37

Giorgio Inghirami

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Sabine Lagger

Sabine Lagger

15

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Olaf Merkel

Olaf Merkel

6

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Thomas Weichhart

Thomas Weichhart

22

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Robert Eferl

Robert Eferl

32

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Enzo Medico

Enzo Medico

29

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Gerda Egger

Gerda Egger

33

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Lukas Kenner

Lukas Kenner

38

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Stefano A Pileri

17

Stefano Pileri

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10 September 2017

18

Pier Paolo Piccaluga

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Bruce A Ruggeri

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Mangeng Cheng

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Philipp B Staber

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Daniela Laimer

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Melanie R Hassler

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Christiane Thallinger

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Christiane Thallinger

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7

Ana-Iris Schiefer

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5

Michaela Schlederer

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10 September 2017

Ingrid Simonitsch-Klupp

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Ingrid Simonitsch-Klupp

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Veronika Sexl

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Karoline Kollmann

3

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Paul W Vesely

4

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Susi Heider

9

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Lena Amenitsch

10

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Matthias Artaker

14

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Peter Valent

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Katia Messana

20

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Indira Landra

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Medhat Shehata

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Maria Todaro

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Gerald Höfler

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Ulrich Jaeger

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10 September 2017

Giorgio Inghirami

37

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10 September 2017

language of work or name

English

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publication date

14 October 2012

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10 September 2017

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10 September 2017

volume

18

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10 September 2017

issue

11

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10 September 2017

page(s)

1699-1704

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https://scigraph.springernature.com/pub.10.1038/nm.2966

10 September 2017

exact match

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cites work

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

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Oncogenic mutations of ALK kinase in neuroblastoma

21 January 2018

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Activating mutations in ALK provide a therapeutic target in neuroblastoma

21 January 2018

1 reference

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

21 January 2018

1 reference

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

21 January 2018

1 reference

Crizotinib in anaplastic large-cell lymphoma

21 January 2018

1 reference

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

21 January 2018

1 reference

EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors.

21 January 2018

1 reference

Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.

21 January 2018

1 reference

The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling

21 January 2018

1 reference

NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.

21 January 2018

1 reference

MatInspector and beyond: promoter analysis based on transcription factor binding sites

21 January 2018

1 reference

A user's guide to the encyclopedia of DNA elements (ENCODE)

21 January 2018

1 reference

Role of platelet-derived growth factors in physiology and medicine

21 January 2018

1 reference

Signal transduction by the PDGF receptors

21 January 2018

1 reference

Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis.

21 January 2018

1 reference

Imatinib targets other than bcr/abl and their clinical relevance in myeloid disorders

21 January 2018

1 reference

Inhibition of tyrosine kinase activity induces caspase-dependent apoptosis in anaplastic large cell lymphoma with NPM-ALK (p80) fusion protein

21 January 2018

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Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib

21 January 2018

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The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRbeta and FIP1L1-PDGFRalpha in vitro and in vivo

21 January 2018

1 reference

Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells

21 January 2018

1 reference

A novel role for IL-22R1 as a driver of inflammation

21 January 2018

1 reference

Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model.

21 January 2018

1 reference

CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers

21 January 2018

1 reference

Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma

21 January 2018

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Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets

21 January 2018

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Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma.

21 January 2018

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Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

21 January 2018

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Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

21 January 2018

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Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

21 January 2018

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Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

21 January 2018

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ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes

21 January 2018

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Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

21 January 2018

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Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.

21 January 2018

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Structural Insights into the ATP Binding Pocket of the Anaplastic Lymphoma Kinase by Site-Directed Mutagenesis, Inhibitor Binding Analysis, and Homology Modeling

21 January 2018

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CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features

21 January 2018

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12 December 2020

Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy

1 reference

12 December 2020

Primary Ki-1-positive anaplastic large-cell lymphoma: a distinct clinicopathologic entity

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12 December 2020

The human genome browser at UCSC

1 reference

12 December 2020

Ki-1/CD30+ (anaplastic) large-cell lymphoma: maturation of a clinicopathologic entity with prospects of effective therapy

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12 December 2020

Identifiers

DOI

10.1038/NM.2966

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Dimensions Publication ID

10 September 2017

1019523037

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Fatcat ID

release_fhntqk53nrfgrev52okn5gpoqm

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1 reference