(Q39259767)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

John H Schwartz

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Steven C Borkan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Zhijian Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Zhiyong Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Jody L Martin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Venugopal Botla

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Kathleen Ruchalski

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

language of work or name

English

0 references

publication date

25 February 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

3 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

volume

283

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

page(s)

12305-12313

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

3 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2431006/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Heat shock protein 27: its potential role in vascular disease

1 reference

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Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.

10 September 2017

1 reference

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Kinase signaling cascades in the mitochondrion: a matter of life or death.

10 September 2017

1 reference

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Bax interacts with the voltage-dependent anion channel and mediates ethanol-induced apoptosis in rat hepatocytes

10 September 2017

1 reference

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HSP72 inhibits apoptosis-inducing factor release in ATP-depleted renal epithelial cells

10 September 2017

1 reference

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The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death

10 September 2017

1 reference

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Hsp27 as a negative regulator of cytochrome C release

10 September 2017

1 reference

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A mitochondrial perspective on cell death

10 September 2017

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The biochemistry of apoptosis

10 September 2017

1 reference

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Hsp27 negatively regulates cell death by interacting with cytochrome c.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Apoptotic mechanisms in acute renal failure

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Prior heat stress inhibits apoptosis in adenosine triphosphate-depleted renal tubular cells

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Regulated targeting of BAX to mitochondria.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Cadherin-catenin complex: protein interactions and their implications for cadherin function

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex

10 September 2017

1 reference

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The src-family kinase inhibitor PP2 suppresses the in vitro invasive phenotype of bladder carcinoma cells via modulation of Akt.

14 September 2017

1 reference

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Possible involvement of phosphatidylinositol 3-kinase/Akt signal pathway in vasopressin-induced HSP27 phosphorylation in aortic smooth muscle A10 cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Proteinase suppression by E-cadherin-mediated cell-cell attachment in premalignant oral keratinocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

The permeability transition pore signals apoptosis by directing Bax translocation and multimerization.

25 September 2017

1 reference

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Bcl-2 prevents Bax oligomerization in the mitochondrial outer membrane

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Phosphatidylinositol 3-kinase is required for adherens junction-dependent mammary epithelial cell spheroid formation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Selective degradation of E-cadherin and dissolution of E-cadherin-catenin complexes in epithelial ischemia

25 September 2017

1 reference

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Heat shock proteins delivered with a virus vector can protect cardiac cells against apoptosis as well as against thermal or hypoxic stress

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Heat stress protein-associated cytoprotection of inner medullary collecting duct cells from rat kidney

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death

25 September 2017

1 reference

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Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Prior heat stress enhances survival of renal epithelial cells after ATP depletion.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Distinct hsp70 domains mediate apoptosis-inducing factor release and nuclear accumulation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold preservation time in rats

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

GSK3 and PKB/Akt are associated with integrin-mediated regulation of PTHrP, IL-6 and IL-8 expression in FG pancreatic cancer cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Overexpression of wild-type heat shock protein 27 and a nonphosphorylatable heat shock protein 27 mutant protects against ischemia/reperfusion injury in a transgenic mouse model

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

ATP depletion of tubular cells causes dissociation of the zonula adherens and nuclear translocation of beta-catenin and LEF-1.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Hsp27 inhibits cytochrome c-mediated caspase activation by sequestering both pro-caspase-3 and cytochrome c.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

HSP27 inhibits cytochrome c-dependent activation of procaspase-9.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

ATP depletion increases tyrosine phosphorylation of beta-catenin and plakoglobin in renal tubular cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Small heat shock proteins and protection against ischemic injury in cardiac myocytes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

Influence of phosphorylation and oligomerization on the protective role of the small heat shock protein 27 in rat adult cardiomyocytes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2431006

HSP27 as a mediator of confluence-dependent resistance to cell death induced by anticancer drugs

2 December 2018

1 reference

12 December 2020

Role of superoxide in apoptosis induced by growth factor withdrawal

1 reference

12 December 2020

Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury

1 reference

12 December 2020

Apoptotic cell death is initiated during normothermic ischemia in human kidneys

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M801291200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299320%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference