(Q39262361)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

mTORC1 is a target of nordihydroguaiaretic acid to prevent breast tumor growth in vitro and in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

nordihydroguaiaretic acid

10 March 2020

main subject

1 reference

ChEBI release 2020-05-28

1 reference

9

1 reference

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10 March 2020

Xiaochun Bai

13

1 reference

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10 March 2020

author name string

Yue Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Song Xu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Jun Lin

3

1 reference

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10 March 2020

Guangyu Yao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Zelong Han

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Bo Liang

6

1 reference

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10 March 2020

Zhenhong Zou

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Zhenguo Chen

8

1 reference

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10 March 2020

Yifan Dai

10

1 reference

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10 March 2020

Tianming Gao

11

1 reference

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10 March 2020

Anling Liu

12

1 reference

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10 March 2020

language of work or name

English

0 references

publication date

29 September 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

Breast Cancer Research and Treatment

10 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

136

1 reference

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10 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

page(s)

379-388

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s10549-012-2270-7

10 March 2020

exact match

0 references

cites work

Nordihydroguaiaretic acid blocks protein transport in the secretory pathway causing redistribution of Golgi proteins into the endoplasmic reticulum.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Prooxidant activity and toxicity of nordihydroguaiaretic acid in clone-9 rat hepatocyte cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Nordihydroguaiaretic acid-induced Ca2+ handling and cytotoxicity in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Mechanisms of nordihydroguaiaretic acid-induced growth inhibition and apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

mTOR: from growth signal integration to cancer, diabetes and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

An expanding role for mTOR in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

mTOR signaling at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Key factors in mTOR regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

mTOR and cancer: many loops in one pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Targeting mTOR signaling for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Multi-mechanisms are involved in reactive oxygen species regulation of mTORC1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Rheb GTPase controls apoptosis by regulating interaction of FKBP38 with Bcl-2 and Bcl-XL

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Cell cycle, CDKs and cancer: a changing paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Molecular mechanisms of mTOR-mediated translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Hypoxia signalling through mTOR and the unfolded protein response in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Nordihydroguaiaretic acid, a cytotoxic insulin-like growth factor-I receptor/HER2 inhibitor in trastuzumab-resistant breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Nordihydroguaiaretic acid inhibits transforming growth factor beta type 1 receptor activity and downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Mechanisms of mTOR inhibitor resistance in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

Targeting TOR dependence in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2270-7

10.1007/S10549-012-2270-7

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23053656%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference