(Q39279213)

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S632A3, a new glutarimide antibiotic, suppresses lipopolysaccharide-induced pro-inflammatory responses via inhibiting the activation of glycogen synthase kinase 3β.

scientific article published on 10 September 2012

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13 February 2020

S632A3, a new glutarimide antibiotic, suppresses lipopolysaccharide-induced pro-inflammatory responses via inhibiting the activation of glycogen synthase kinase 3β (English)

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13 February 2020

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lipopolysaccharide

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13 February 2020

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Na Zhang

2

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13 February 2020

Yan Wang

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13 February 2020

Jinjing Chen

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13 February 2020

Jiajia Shen

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13 February 2020

Zhen Wang

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13 February 2020

Rong Xu

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13 February 2020

Jingpu Zhang

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13 February 2020

Danqing Song

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13 February 2020

Diandong Li

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13 February 2020

Experimental Cell Research

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13 February 2020

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13 February 2020

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13 February 2020

2592-2603

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13 February 2020

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Isolation, structure determination and biological activity of a new glutarimide antibiotic, S632A3

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Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription

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Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes

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Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor

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10.1016/J.YEXCR.2012.08.008

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22975730%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22975730%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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