(Q39284845)

10 September 2017

title

Design and synthesis of 3-carbamoylbenzoic acid derivatives as inhibitors of human apurinic/apyrimidinic endonuclease 1 (APE1). (English)

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10 September 2017

Francesca Aiello

1

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10 September 2017

Yumna Shabaik

2

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10 September 2017

Adrian Esqueda

3

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10 September 2017

Tino W Sanchez

4

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10 September 2017

Fedora Grande

5

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10 September 2017

Antonio Garofalo

6

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10 September 2017

Nouri Neamati

7

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10 September 2017

publication date

5 September 2012

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10 September 2017

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10 September 2017

volume

7

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10 September 2017

issue

10

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10 September 2017

page(s)

1825-1839

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Instability and decay of the primary structure of DNA

10 September 2017

cites work

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https://api.crossref.org/works/10.1002%2FCMDC.201200334

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Long patch base excision repair compensates for DNA polymerase β inactivation by the C4'-oxidized abasic site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

The many functions of APE1/Ref-1: not only a DNA repair enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Going ape as an approach to cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Reduced expression of DNA repair and redox signaling protein APE1/Ref-1 impairs human pancreatic cancer cell survival, proliferation, and cell cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Radiation resistance in glioma cells determined by DNA damage repair activity of Ape1/Ref-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Subcellular localization of APE1/Ref-1 in human hepatocellular carcinoma: possible prognostic significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Prognostic significance of APE1 cytoplasmic localization in human epithelial ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: a scaffold hopping approach using salicylate and catechol groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Amino acid binding by 2-(guanidiniocarbonyl)pyridines in aqueous solvents: a comparative binding study correlating complex stability with stereoelectronic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

5-Substituted-1H-tetrazoles as carboxylic acid isosteres: medicinal chemistry and synthetic methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

5-Fluorouracil is efficiently removed from DNA by the base excision and mismatch repair systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

Preclinical evaluation of novel triphenylphosphonium salts with broad-spectrum activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200334

21 January 2018

Identifiers

DOI

10.1002/CMDC.201200334

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release_gub3dhel45cvbi72hx6cwpxj6q

10 September 2017

Fatcat ID

0 references

1 reference