(Q39285833)

10 September 2017

title

Stearoyl-CoA desaturase activity modulates the activation of epidermal growth factor receptor in human lung cancer cells (English)

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10 September 2017

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Mary Nashed

1

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10 September 2017

Jeffrey W Chisholm

series ordinal

2

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10 September 2017

R Ariel Igal

series ordinal

3

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10 September 2017

language of work or name

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3 September 2012

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Experimental Biology and Medicine

10 September 2017

published in

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10 September 2017

volume

237

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10 September 2017

issue

9

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10 September 2017

page(s)

1007-1017

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Hallmarks of Cancer: The Next Generation

10 September 2017

cites work

1 reference

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Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer

21 January 2018

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Fatty acid synthesis: a potential selective target for antineoplastic therapy

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RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells

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ATP citrate lyase is an important component of cell growth and transformation

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Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival

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Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

21 January 2018

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Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy

21 January 2018

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Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells

21 January 2018

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Stearoyl-CoA desaturase is involved in the control of proliferation, anchorage-independent growth, and survival in human transformed cells

21 January 2018

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Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPK

21 January 2018

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Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells

21 January 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

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Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice

21 January 2018

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Epidermal growth factor receptor dependence in human tumors: more than just expression?

21 January 2018

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ErbB receptors and signaling pathways in cancer

21 January 2018

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Somatic mutations affect key pathways in lung adenocarcinoma

21 January 2018

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HER-2, EGFR, COX-2 expression status correlated to microvessel density and survival in resected non-small cell lung cancer

21 January 2018

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Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

21 January 2018

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Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

21 January 2018

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Epidermal growth factor receptors are localized to lipid rafts that contain a balance of inner and outer leaflet lipids: a shotgun lipidomics study

21 January 2018

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The challenge of lipid rafts

21 January 2018

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Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking

21 January 2018

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Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins

21 January 2018

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Novel, potent, selective, and metabolically stable stearoyl-CoA desaturase (SCD) inhibitors

21 January 2018

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Orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors.

21 January 2018

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Ligand-independent activation of the EGFR by lipid raft disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Roles of StearoylCoA Desaturase-1 in the Regulation of Cancer Cell Growth, Survival and Tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Epidermal growth factor receptor: mechanisms of activation and signalling.

21 January 2018

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https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Signaling through ERBB receptors: multiple layers of diversity and control

21 January 2018

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Neuregulins: functions, forms, and signaling strategies

21 January 2018

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Endocytosis and intracellular trafficking of ErbBs

21 January 2018

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The TOR pathway: a target for cancer therapy

21 January 2018

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The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

21 January 2018

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https://api.crossref.org/works/10.1258%2FEBM.2012.012126

PI3K pathway alterations in cancer: variations on a theme

21 January 2018

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https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Oleic acid enhances vascular smooth muscle cell proliferation via phosphatidylinositol 3-kinase/Akt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

A role for protein phosphatase 2A-like activity, but not atypical protein kinase Czeta, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Cell membrane fluidity and prognosis of lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Effect of membrane fluidity on tyrosine kinase activity of reconstituted epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Mitochondrial oxidative stress is modulated by oleic acid via an epidermal growth factor receptor-dependent activation of glutathione peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

The "Gab" in signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Brick by brick: metabolism and tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Ras proteins: different signals from different locations

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

Spatiotemporal analysis of differential Akt regulation in plasma membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1258%2FEBM.2012.012126

21 January 2018

Identifiers

DOI

10.1258/EBM.2012.012126

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10 September 2017

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