(Q39297983)

10 September 2017

Stimulation of the retinoid X receptor facilitates beta-amyloid clearance across the blood-brain barrier (English)

1 reference

10 September 2017

1 reference

Corbin Bachmeier

1

1 reference

10 September 2017

David Beaulieu-Abdelahad

2

1 reference

10 September 2017

Fiona Crawford

3

1 reference

10 September 2017

Michael Mullan

4

1 reference

10 September 2017

Daniel Paris

5

1 reference

10 September 2017

14 August 2012

1 reference

Journal of Molecular Neuroscience

10 September 2017

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10 September 2017

49

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10 September 2017

2

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10 September 2017

270-276

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https://scigraph.springernature.com/pub.10.1007/s12031-012-9866-6

10 September 2017

0 references

cites work

Characterization and use of human brain microvascular endothelial cells to examine β-amyloid exchange in the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Regulation of P-glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

The retinoid X receptors and their ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

All-trans retinoic acid enhances the transport of phase II metabolites of benzo[a]pyrene by inducing the Breast Cancer Resistance Protein expression in Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

ApoE promotes the proteolytic degradation of Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

The role of apolipoprotein E in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Secretion of apolipoprotein E from macrophages occurs via a protein kinase A and calcium-dependent pathway along the microtubule network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Regulation of endogenous apolipoprotein E secretion by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Intracellular amyloid-beta in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Retinoid X receptors: common heterodimerization partners with distinct functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

A liver X receptor and retinoid X receptor heterodimer mediates apolipoprotein E expression, secretion and cholesterol homeostasis in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Cell surface proteoglycans modulate net synthesis and secretion of macrophage apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Decreased clearance of CNS beta-amyloid in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Amyloid beta protein as a marker or risk factor of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Amyloid imaging in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Systemic treatment with liver X receptor agonists raises apolipoprotein E, cholesterol, and amyloid-β peptides in the cerebral spinal fluid of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Peroxisome proliferator-activated receptor-gamma regulates the expression and function of very-low-density lipoprotein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Cognitive deficit in amyloid-beta-injected mice was improved by pretreatment with a low dose of telmisartan partly because of peroxisome proliferator-activated receptor-gamma activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Peroxisome proliferator-activated receptor {gamma} stimulation of adipocyte ApoE gene transcription mediated by the liver receptor X pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Understanding the basis for the association of apoE4 with Alzheimer's disease: opening the door for therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Amyloid β-protein precursor and apolipoprotein E production in cultured cerebral endothelial cells isolated from brains of patients with neurodegenerative disorders at autopsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-012-9866-6

Epitope-dependent effects of Beta-amyloid antibodies on Beta-amyloid clearance in an in vitro model of the blood-brain barrier

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22890420

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dynamic and stable pools of apoE differ functionally at the HepG2 cell surface.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22890420

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

ABCG2- and ABCG4-mediated efflux of amyloid-β peptide 1-40 at the mouse blood-brain barrier

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22890420

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12031-012-9866-6

1 reference

10 September 2017

1 reference