(Q39553531)

13 September 2017

title

Regulation of P-glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells (English)

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13 September 2017

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Carolyn L Cummins

3

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author name string

Gary N Y Chan

series ordinal

1

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13 September 2017

Md Tozammel Hoque

series ordinal

2

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13 September 2017

Reina Bendayan

series ordinal

4

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13 September 2017

language of work or name

English

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publication date

25 May 2011

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Journal of Neurochemistry

13 September 2017

published in

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13 September 2017

volume

118

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13 September 2017

issue

2

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13 September 2017

page(s)

163-175

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Structure and function of the blood-brain barrier

13 September 2017

cites work

1 reference

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In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation.

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Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier

21 January 2018

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Functional expression and localization of P-glycoprotein at the blood brain barrier

21 January 2018

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Peptide mimetic HIV protease inhibitors are ligands for the orphan receptor SXR.

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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

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A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor

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St Johns wort increases expression of P-glycoprotein: implications for drug interactions

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The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

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Nuclear translocation of adenoviral-enhanced yellow fluorescent protein-tagged-human constitutive androstane receptor (hCAR): a novel tool for screening hCAR activators in human primary hepatocytes

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Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes

21 January 2018

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Interplay between the nuclear receptor pregnane X receptor and the uptake transporter organic anion transporter polypeptide 1A2 selectively enhances estrogen effects in breast cancer

21 January 2018

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Steroid and xenobiotic receptor (SXR), cytochrome P450 3A4 and multidrug resistance gene 1 in human adult and fetal tissues

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21 January 2018

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Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors

21 January 2018

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21 January 2018

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Pregnane X receptor (PXR) regulates P-glycoprotein at the blood-brain barrier: functional similarities between pig and human PXR.

21 January 2018

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Biopharmaceutical drug targeting to the brain

21 January 2018

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Induction of P-glycoprotein expression and activity by ritonavir in bovine brain microvessel endothelial cells

21 January 2018

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Involvement of P-glycoprotein in the transport of saquinavir and indinavir in rat brain microvessel endothelial and microglia cell lines

21 January 2018

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Regulation of multidrug resistance protein 1 by tumor necrosis factor alpha in cultured glial cells: involvement of nuclear factor-kappaB and c-Jun N-terminal kinase signaling pathways

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21 January 2018

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P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

21 January 2018

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21 January 2018

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The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

21 January 2018

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CAR and PXR: the xenobiotic-sensing receptors

21 January 2018

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P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

21 January 2018

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21 January 2018

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Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

21 January 2018

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The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver

21 January 2018

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Blood-brain barrier-specific properties of a human adult brain endothelial cell line

21 January 2018

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1096/FJ.04-3458FJE

Identifiers

DOI

10.1111/J.1471-4159.2011.07288.X

1 reference

13 September 2017

1 reference