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Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
18349876
retrieved
31 January 2017
title
Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier
(English)
1 reference
stated in
PubMed
PubMed ID
18349876
retrieved
31 January 2017
main subject
brain
0 references
blood–brain barrier
1 reference
based on heuristic
inferred from title
author
David S. Miller
series ordinal
6
object named as
David S. Miller
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PubMed
PubMed ID
18349876
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31 January 2017
author name string
Björn Bauer
series ordinal
1
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PubMed
PubMed ID
18349876
retrieved
31 January 2017
Anika M. S. Hartz
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
18349876
retrieved
31 January 2017
Jonathan R. Lucking
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3
1 reference
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PubMed
PubMed ID
18349876
retrieved
31 January 2017
Xiaodong Yang
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
18349876
retrieved
31 January 2017
Gary M. Pollack
series ordinal
5
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PubMed
PubMed ID
18349876
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31 January 2017
publication date
1 June 2008
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PubMed
PubMed ID
18349876
retrieved
31 January 2017
published in
Journal of Cerebral Blood Flow & Metabolism
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stated in
PubMed
PubMed ID
18349876
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31 January 2017
volume
28
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PubMed
PubMed ID
18349876
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31 January 2017
page(s)
1222–1234
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PubMed
PubMed ID
18349876
retrieved
31 January 2017
issue
6
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stated in
PubMed
PubMed ID
18349876
retrieved
31 January 2017
cites work
Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier.
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In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation.
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Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier.
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Drug metabolizing enzyme activities and superoxide formation in primary and immortalized rat brain endothelial cells
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Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects.
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Nuclear receptors and the control of metabolism
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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
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Regulation of CYP3A4 by the bile acid receptor FXR: evidence for functional binding sites in the CYP3A4 gene
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Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1.
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Rapid modulation of P-glycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide.
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The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage
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Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats.
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Expression of rat Multidrug Resistance Protein 2 (Mrp2) in male and female rats during normal and pregnenolone-16alpha-carbonitrile (PCN)-induced postnatal ontogeny
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The role of protein synthesis and degradation in the post-transcriptional regulation of rat multidrug resistance-associated protein 2 (Mrp2, Abcc2)
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Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor
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The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism
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An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway
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The MRP family of drug efflux pumps
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Regulation of drug and bile salt transporters in liver and intestine
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Mrp4 confers resistance to topotecan and protects the brain from chemotherapy
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Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
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Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required
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Drug resistance in brain diseases and the role of drug efflux transporters.
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Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases
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Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
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Xenobiotic efflux pumps in isolated fish brain capillaries
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Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators
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Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor
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Molecular aspects of renal anionic drug transport
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Modulation of P-glycoprotein expression by cytochrome P450 3A inducers in male and female rat livers.
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Role of Multidrug Resistance Protein 2 (MRP2, ABCC2) in Alkylating Agent Detoxification: MRP2 Potentiates GlutathioneS-Transferase A1-1-Mediated Resistance to Chlorambucil Cytotoxicity
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Involvement of multidrug resistance associated protein 1 (Mrp1) in the efflux transport of 17beta estradiol-D-17beta-glucuronide (E217betaG) across the blood-brain barrier
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Induction of ABCC3 (MRP3) by pregnane X receptor activators
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1 reference
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1 reference
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Crossref
reference URL
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Identifiers
DOI
10.1038/JCBFM.2008.16
1 reference
stated in
PubMed
PubMed ID
18349876
retrieved
31 January 2017
PubMed ID
18349876
1 reference
stated in
PubMed
PubMed ID
18349876
retrieved
31 January 2017
ResearchGate publication ID
5502300
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