(Q39305402)

10 September 2017

title

Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma (English)

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10 September 2017

U Schmitz

2

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Olaf Wolkenhauer

object named as

O Wolkenhauer

3

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author name string

A Bhattacharya

1

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10 September 2017

M Schönherr

4

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10 September 2017

Y Raatz

5

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10 September 2017

M Kunz

6

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10 September 2017

language of work or name

English

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publication date

30 July 2012

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10 September 2017

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10 September 2017

volume

32

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10 September 2017

issue

26

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10 September 2017

page(s)

3175-3183

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https://scigraph.springernature.com/pub.10.1038/onc.2012.324

10 September 2017

exact match

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cites work

Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.324

In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.324

Novel genes associated with malignant melanoma but not benign melanocytic lesions

21 January 2018

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Inhibition of proteasome-dependent degradation of Wee1 in G2-arrested Hep3B cells by TGF beta 1.

21 January 2018

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MicroRNAs: target recognition and regulatory functions

21 January 2018

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Oncomirs - microRNAs with a role in cancer

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Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis

21 January 2018

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Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

21 January 2018

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Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

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OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.

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miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma.

21 January 2018

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Efficient tumour formation by single human melanoma cells

21 January 2018

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The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms

21 January 2018

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Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma.

21 January 2018

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Signatures of microRNAs and selected microRNA target genes in human melanoma.

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microRNAs regulate human embryonic stem cell division

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miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells.

21 January 2018

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Patterns of expression of DNA repair genes and relapse from melanoma

21 January 2018

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MicroRNAs and the cell cycle

21 January 2018

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Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer

21 January 2018

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MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells.

21 January 2018

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A microRNA polycistron as a potential human oncogene

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c-Myc-regulated microRNAs modulate E2F1 expression

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microRNAs exhibit high frequency genomic alterations in human cancer

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A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation

21 January 2018

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Positive regulation of Wee1 by Chk1 and 14-3-3 proteins

21 January 2018

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Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells

21 January 2018

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Transcriptional repression of WEE1 by Kruppel-like factor 2 is involved in DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.324

Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents

21 January 2018

1 reference

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MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo

21 January 2018

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Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase.

21 January 2018

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Hallmarks of Cancer: The Next Generation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.324

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.324

Small RNAs with big impacts

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.324

Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.324

The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.324

microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.324

MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.324

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.324

1 reference

10 September 2017

1 reference