(Q39309125)

10 September 2017

title

Screening of siRNA nanoparticles for delivery to airway epithelial cells using high-content analysis (English)

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10 September 2017

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Alan Hibbitts

1

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James W Barlow

object named as

James Barlow

5

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Warren Thomas

object named as

Warren Thomas

4

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Sally-Ann Cryan

object named as

Sally-Ann Cryan

7

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author name string

Alan Hibbitts

1

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10 September 2017

Nora Lieggi

2

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10 September 2017

Olive McCabe

3

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10 September 2017

Warren Thomas

4

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10 September 2017

James Barlow

5

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10 September 2017

Fiona O'Brien

6

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10 September 2017

Sally-Ann Cryan

7

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10 September 2017

Fiona O’Brien

6

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publication date

1 August 2011

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10 September 2017

August 2011

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published in

Therapeutic delivery

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10 September 2017

volume

2

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10 September 2017

issue

8

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10 September 2017

page(s)

987-999

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RNA interference is mediated by 21- and 22-nucleotide RNAs

10 September 2017

cites work

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Recent progress in gene delivery using non-viral transfer complexes

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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Mitochondria and apoptosis

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Delivery of RNA interference

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Visualizing a Correlation between siRNA Localization, Cellular Uptake, and RNAi in Living Cells

21 January 2018

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Comparative evaluation of target-specific GFP gene silencing efficiencies for antisense ODN, synthetic siRNA, and siRNA plasmid complexed with PEI-PEG-FOL conjugate

21 January 2018

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Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

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siRNA and the lung: research tool or therapeutic drug?

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Pulmonary delivery of nucleic acids

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Extracellular barriers in respiratory gene therapy.

21 January 2018

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Advances in high content screening for drug discovery

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Inflammatory pathway analysis using a high content screening platform

21 January 2018

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High-throughput RNAi screening to dissect cellular pathways: a how-to guide.

21 January 2018

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A novel high-throughput assay for the quantitative assessment of receptor trafficking

21 January 2018

1 reference

High content analysis of cytotoxic effects of pDMAEMA on human intestinal epithelial and monocyte cultures

21 January 2018

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High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

21 January 2018

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Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures

21 January 2018

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Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

21 January 2018

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Gold nanoshells in cancer imaging and therapy: towards clinical application.

21 January 2018

1 reference

Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.

21 January 2018

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PEGylation affects cytotoxicity and cell-compatibility of poly(ethylene imine) for lung application: structure-function relationships

21 January 2018

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Culture of Calu-3 cells at the air interface provides a representative model of the airway epithelial barrier

21 January 2018

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Reverse transcription-polymerase chain reaction (RT-PCR) phenotypic analysis of cell cultures of human tracheal epithelium, tracheobronchial glands, and lung carcinomas

21 January 2018

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Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3.

21 January 2018

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Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction

21 January 2018

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Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes

21 January 2018

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Biophysical and structural characterization of polyethylenimine-mediated siRNA delivery in vitro.

21 January 2018

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Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emissi

21 January 2018

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Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes

21 January 2018

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Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system

21 January 2018

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Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung

21 January 2018

1 reference

Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance.

21 January 2018

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Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice.

21 January 2018

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Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance.

21 January 2018

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Performance of the vibrating membrane aerosol generation device: Aeroneb Micropump Nebulizer

21 January 2018

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21 January 2018

Identifiers

DOI

10.4155/TDE.11.73

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