(Q39325795)

11 September 2017

title

Promotion of adiponectin multimerization by emodin: a novel AMPK activator with PPARγ-agonist activity (English)

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11 September 2017

Zhifen Chen

1

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11 September 2017

Lu Zhang

2

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11 September 2017

Junyang Yi

3

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11 September 2017

Zhuanbo Yang

4

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11 September 2017

Zhijie Zhang

5

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11 September 2017

Zhen Li

6

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11 September 2017

publication date

1 November 2012

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Journal of Cellular Biochemistry

11 September 2017

published in

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11 September 2017

volume

113

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11 September 2017

issue

11

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11 September 2017

page(s)

3547-3558

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Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

11 September 2017

cites work

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Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects

21 January 2018

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Changes of adiponectin oligomer composition by moderate weight reduction

21 January 2018

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Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?

21 January 2018

1 reference

Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin

21 January 2018

1 reference

AMPK activation regulates apoptosis, adipogenesis, and lipolysis by eIF2alpha in adipocytes

21 January 2018

1 reference

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

21 January 2018

1 reference

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

21 January 2018

1 reference

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation

21 January 2018

1 reference

Emodin inhibits TNF-alpha-induced human aortic smooth-muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis.

21 January 2018

1 reference

Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

21 January 2018

1 reference

AdipoQ is a novel adipose-specific gene dysregulated in obesity

21 January 2018

1 reference

Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

21 January 2018

1 reference

Emodin, a protein tyrosine kinase inhibitor from Polygonum cuspidatum

21 January 2018

1 reference

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

21 January 2018

1 reference

Berberine activates GLUT1-mediated glucose uptake in 3T3-L1 adipocytes

21 January 2018

1 reference

Disturbed secretion of mutant adiponectin associated with the metabolic syndrome

21 January 2018

1 reference

Adiponectin multimer distribution in patients with familial combined hyperlipidemia.

21 January 2018

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Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake

21 January 2018

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Adipokines as emerging mediators of immune response and inflammation.

21 January 2018

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Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states

21 January 2018

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Activation of AMPK by berberine promotes adiponectin multimerization in 3T3-L1 adipocytes

21 January 2018

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Polygoni cuspidati radix inhibits the activation of Syk kinase in mast cells for antiallergic activity

21 January 2018

1 reference

Transcriptional and post-translational regulation of adiponectin

21 January 2018

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A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization

21 January 2018

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Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma

21 January 2018

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Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation.

21 January 2018

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PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

21 January 2018

1 reference

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

21 January 2018

1 reference

Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity

21 January 2018

1 reference

Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity

21 January 2018

1 reference

Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-L alpha.

21 January 2018

1 reference

Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosis

21 January 2018

1 reference

Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family.

21 January 2018

1 reference

Antiatherogenic effect of pioglitazone in type 2 diabetic patients irrespective of the responsiveness to its antidiabetic effect

21 January 2018

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A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

21 January 2018

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AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling

21 January 2018

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Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways

21 January 2018

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Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action

21 January 2018

1 reference

Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin.

21 January 2018

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Post-translational modifications of adiponectin: mechanisms and functional implications.

21 January 2018

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Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention.

21 January 2018

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Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes

21 January 2018

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Diabetes is an inflammatory disease: evidence from traditional Chinese medicines

21 January 2018

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Anti-diabetic effects of emodin involved in the activation of PPARgamma on high-fat diet-fed and low dose of streptozotocin-induced diabetic mice

21 January 2018

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

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Emodin with PPARgamma ligand-binding activity promotes adipocyte differentiation and increases glucose uptake in 3T3-Ll cells.

21 January 2018

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Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties.

21 January 2018

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Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCB.24232

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11 September 2017

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