(Q39329034)

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Alveolar rhabdomyosarcoma-associated proteins PAX3/FOXO1A and PAX7/FOXO1A suppress the transcriptional activity of MyoD-target genes in muscle stem cells.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22710712%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Alveolar rhabdomyosarcoma-associated proteins PAX3/FOXO1A and PAX7/FOXO1A suppress the transcriptional activity of MyoD-target genes in muscle stem cells (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22710712%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

rhabdomyosarcoma

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based on heuristic

inferred from title

Frédéric Relaix

4

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5 February 2020

5

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5 February 2020

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F Calhabeu

1

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5 February 2020

S Hayashi

2

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5 February 2020

J E Morgan

3

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5 February 2020

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18 June 2012

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5 February 2020

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5 February 2020

32

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5 February 2020

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5 February 2020

651-662

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5 February 2020

https://scigraph.springernature.com/pub.10.1038/onc.2012.73

0 references

Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

The oncogenic fusion protein Pax3-FKHR has a greater post-translational stability relative to Pax3 during early myogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

A Pax3/Pax7-dependent population of skeletal muscle progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Pax7 and myogenic progression in skeletal muscle satellite cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Muscle satellite cells adopt divergent fates: a mechanism for self-renewal?

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Genome-Wide Identification of PAX3-FKHR Binding Sites in Rhabdomyosarcoma Reveals Candidate Target Genes Important for Development and Cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Disruption of the MyoD/p21 Pathway in Rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Common musculoskeletal tumors of childhood and adolescence

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Evaluation of new monoclonal anti-MyoD1 and anti-myogenin antibodies for the diagnosis of rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Biomarker system for studying muscle, stem cells, and cancer in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Muscling in: Uncovering the origins of rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Further characterisation of the molecular signature of quiescent and activated mouse muscle satellite cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Pax3 inhibits myogenic differentiation of cultured myoblast cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

The oncogenic transcription factor PAX3-FKHR can convert fibroblasts into contractile myotubes.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

MyoD and the transcriptional control of myogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Direct isolation of satellite cells for skeletal muscle regeneration.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Regulation of MyoD function in the dividing myoblast

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

The circuitry of a master switch: Myod and the regulation of skeletal muscle gene transcription

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Integrated functions of Pax3 and Pax7 in the regulation of proliferation, cell size and myogenic differentiation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Divergent functions of murine Pax3 and Pax7 in limb muscle development

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

In vitro transcription system delineates the distinct roles of the coactivators pCAF and p300 during MyoD/E47-dependent transactivation.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Phosphorylation of nuclear MyoD is required for its rapid degradation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Identification of a new class of PAX3-FKHR target promoters: a role of the Pax3 paired box DNA binding domain

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Muscle satellite cells are a functionally heterogeneous population in both somite-derived and branchiomeric muscles.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Comparative expression analysis of Pax3 and Pax7 during mouse myogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Common and variant gene fusions predict distinct clinical phenotypes in rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Identification of a new hybrid serum response factor and myocyte enhancer factor 2-binding element in MyoD enhancer required for MyoD expression during myogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

A dominant-negative form of transcription factor MEF2 inhibits myogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Epigenetic regulation of skeletal myogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

RNA helicase A mediates association of CBP with RNA polymerase II

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.73

31 March 2020

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