(Q39338816)

11 September 2017

title

Development of a high-content high-throughput screening assay for the discovery of ATM signaling inhibitors (English)

1 reference

11 September 2017

Catherine Bardelle

1

1 reference

11 September 2017

Joanna Boros

series ordinal

2

1 reference

11 September 2017

publication date

31 May 2012

1 reference

Journal of Biomolecular Screening

11 September 2017

published in

1 reference

11 September 2017

volume

17

1 reference

11 September 2017

issue

7

1 reference

11 September 2017

page(s)

912-920

1 reference

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

11 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Dealing with DNA damage: relationships between checkpoint and repair pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Thr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

The DNA-damage response: new molecular insights and new approaches to cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

DNA repair: how to PIKK a partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

DNA double-strand breaks: signaling, repair and the cancer connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Involvement of novel autophosphorylation sites in ATM activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Autophosphorylation and ATM activation: additional sites add to the complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Cell cycle checkpoints: preventing an identity crisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Rapid activation of ATR by ionizing radiation requires ATM and Mre11

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Monitoring ATM kinase activity in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Development of a high-content screening method for chemicals modulating DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

ATM activation by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

ATM, a DNA damage-inducible kinase, contributes to activation by high NaCl of the transcription factor TonEBP/OREBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

Activation of ATM-dependent DNA damage signal pathway by a histone deacetylase inhibitor, trichostatin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112448529

21 January 2018

Identifiers

DOI

10.1177/1087057112448529

1 reference

11 September 2017

1 reference